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Case Reports
. 2021 Jun 5;2(3):562-564.
doi: 10.1002/jha2.247. eCollection 2021 Aug.

Successful treatment of an EBV-positive HIV-associated polymorphic B-cell lymphoproliferative disorder by rituximab monotherapy

Mohamad Sabbah  1 , Sylvain Choquet  1 , Agathe Maillon  2 , Clotilde Bravetti  2 , Marine Baron  1 , Frédéric Charlotte  3 , Damien Roos-Weil  1
Affiliations
Case Reports

Successful treatment of an EBV-positive HIV-associated polymorphic B-cell lymphoproliferative disorder by rituximab monotherapy

Mohamad Sabbah et al. EJHaem. .
No abstract available

Keywords: HIV; polymorphic B‐cell lymphoproliferative disorder; rituximab.

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Conflict of interest statement

The authors declare that there is no conflict of interest that could be perceived as prejudicing the impartiality of the research reported.Mohamad Sabbah, Sylvain Choquet, Agathe Maillon, Clotilde Bravetti, Marine Baron, Frédéric Charlotte, and Damien Roos‐Weil performed, designed the research study, analyzed the data, and wrote the paper.

Figures

FIGURE 1
FIGURE 1
(A) Rectal mass biopsy showed (a) polymorphous infiltrate made up of variable size lymphocytes mixed with plasma cells (H&E staining), (b) CD20‐positive lymphocytes of variable size (CD20 immunostaining), (c) few EBV‐positive cells (EBV in situ hybridization, EBER probe), and polytypic expression of light chain immunoglobulin by plasma cells ((d) kappa and (e) lambda light chain immunostaining). (B) B‐cell clonality profile (Genemapper software): polyclonal aspect at the locus of immunoglobulin heavy chain gene. (C) Computed tomography (CT)‐scan images of rectal mass (indicated by black arrow) before (up) and after (down) rituximab monotherapy. No PET‐scan was available for this patient due to the lack of social security
See this image and copyright information in PMC

References

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