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Randomized Controlled Trial
. 2022 Jun 29:2022:5290813.
doi: 10.1155/2022/5290813. eCollection 2022.

Application of Intravenous Anesthesia in Laparoscopic Hiatal Hernia Repair of Children

Xueli Zhu  1 , Haiyang Yang  1 , Meimin Qu  1 , Jianshe Wang  1 , Jian Fei  1 , Linyu Shi  1
Affiliations
Randomized Controlled Trial

Application of Intravenous Anesthesia in Laparoscopic Hiatal Hernia Repair of Children

Xueli Zhu et al. Contrast Media Mol Imaging. .

Retraction in

Abstract

In order to solve the stress problem in laparoscopic hiatal hernia repair of children, improve surgical safety, and reduce surgical risk, this study compared the perioperative changes of epinephrine, norepinephrine, IL-6, IL-10, and hemodynamics in children undergoing laparoscopic surgery under intravenous general anesthesia and general anesthesia combined with an epidural block. In this study, 40 children aged 1-3 years who planned to undergo laparoscopic ortopexy and those who planned to undergo laparoscopic high ligation of hernia sac, aged 23.84 1.6 months and weighed 14.9 1.1 kg, were randomly divided into general anesthesia combined with the epidural block group (group A) and a total intravenous anesthesia group (group B), with 20 subjects in each group. The results are as follows: There were no differences in age, gender, body weight, anesthesia time, pneumoperitoneum duration, and functional time between the two groups. Cytokines: Compared with T0, the levels of IL-6 in T2, T3, T4, and T5 groups were significantly increased (P < 0.01). IL-10 levels: T2, T3, T4, and T5 groups were further increased, and the difference was statistically significant compared with T0 (P < 0.01). There was no difference between groups (P > 0.05). The recovery time in group B was shorter than that in group A (P < 0.01), and the total amount of propofol and fentanyl in group B was less than that in group A (P < 0.01). Through research on intravenous anesthesia treatment, it has been proved that total intravenous anesthesia can relieve perioperative pressure, reduce intravenous injection, and reduce the recovery time of children. However, its effect on cytokines is not obvious, so intravenous anesthesia is the most appropriate anesthesia mode in laparoscopic hiatal hernia repair surgery, which has practical significance.

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Conflict of interest statement

The authors declare that they have no conflicts of interest.

Figures

Figure 1
Figure 1
Laparoscopic surgery.
Figure 2
Figure 2
Comparison of intraoperative HR between two groups.
Figure 3
Figure 3
Comparison of intraoperative MAP between two groups of children.
See this image and copyright information in PMC

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References

    1. Nagata O., Matsuki Y., Ogino Y., Shigemi K. Safety and efficacy of an automated anesthesia delivery system for total intravenous anesthesia with propofol, remifentanil, and rocuronium: a non-inferiority randomized controlled trial versus manually controlled anesthesia. Journal of Anesthesia . 2022;36(1):96–106. doi: 10.1007/s00540-021-03015-6. - DOI - PubMed
    1. Prakash D., Parate L. H., Nagaraj M. C., Pujari V. S., Dinesh N. The study of intranasal dexmedetomidine during total intravenous anesthesia for endoscopic retrograde cholangiopancreatography. The Indian Anaesthetists Forum . 2021;21(2):129–133.
    1. Chen Y., Wang B., Yao L., Feng Z. Maximum dose of continuous infusion of mivacurium for thyroid surgery under total intravenous anesthesia: a sequential trial of monitoring neurological function in 30 patients. Nan fang yi ke da xue bao = Journal of Southern Medical University . 2021;41(1):64–68. doi: 10.12122/j.issn.1673-4254.2021.01.08. - DOI - PMC - PubMed
    1. Likhvantsev V., Yadgarov M., Di Piazza M., Kadantseva K. Inhalation vs total intravenous anesthesia in cancer surgery: where is the pendulum» now? (Meta-Analysis and review) General Reanimatology . 2021;16(6):91–104. doi: 10.15360/1813-9779-2020-6-91-104. - DOI
    1. Bhattarai R., Hamal P. K. Comparison of fentanyl-propofol and ketamine-propofol combination in induction and maintenance with intravenous anesthesia for short surgical procedures at moderate elevations. Journal of Nepal Health Research Council . 2021;18(4):769–775. doi: 10.33314/jnhrc.v18i4.3323. - DOI - PubMed

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