Minimally Invasive Surgery Periodontal Therapy for the Treatment of Intrabony Periodontal Defects: A Systematic Review
- PMID: 35846580
- PMCID: PMC9285832
- DOI: 10.4103/ccd.ccd_1046_20
Minimally Invasive Surgery Periodontal Therapy for the Treatment of Intrabony Periodontal Defects: A Systematic Review
Abstract
Background: Minimally invasive therapeutic approaches have become the standard of care for many medical procedures. Conventional periodontal surgical therapies involve extensive tissue reflection, resulting in increased morbidity which stands to reason out that Minimally invasive surgery (MIS) approach for periodontal therapy would result in less morbidity and better esthetics for the patient. Thus, the aim of this review is to assess the clinical efficacy of MIS periodontal therapy compared to conventional access flap surgery for the treatment of intrabony periodontal defects.
Materials and methods: An electronic and manual search was done to identify and collect studies evaluating MIS periodontal therapy for the treatment of intrabony periodontal defects in terms of periodontal probing depth (PPD) reduction, clinical attachment level (CAL) gain, and gingival recession (REC) with a minimum of 6 month follow-up published in English. Six studies which satisfied the inclusion criteria were included for the review and the data extracted.
Results: The six included studies contributed to a total of 193 patients who underwent 93 MIS therapies for treating intrabony defects with at least a 6-month follow-up. Clinical evaluation showed a PPD reduction ranging from 3.55 ± 0.88 mm to 5.2 ± 1.6 mm, while CAL gain ranged from 2.82 ± 1.19 mm to 4.5 ± 1.1 mm, while the change in gingival margin level ranged from 0.06 mm to 0.5 mm. Only one study directly compared single flap approach (SFA) (a type of MIS) to double flap approach (papilla preservation flap) which reported PPD reduction and CAL gain to be better in SFA.
Conclusion: Even though the above evidence compels us to believe that minimally invasive periodontal surgery is less invasive, less time consuming, and less morbid, the lack of enough studies directly comparing MIS with conventional access flap surgeries suggest that these conclusions are arbitrary. Thus, there is currently an absence of adequate evidence to substantiate the beneficial effect of minimally invasive periodontal surgical approach compared to a conventional access flap surgery for the treatment of intrabony periodontal defects.
Keywords: Minimally invasive; periodontal regeneration; periodontal surgery.
Copyright: © 2022 Contemporary Clinical Dentistry.
Conflict of interest statement
There are no conflicts of interest.
Figures
Similar articles
-
The role of surgical flap design (minimally invasive flap vs. extended flap with papilla preservation) on the healing of intrabony defects treated with an enamel matrix derivative: a 12-month two-center randomized controlled clinical trial.Clin Oral Investig. 2022 Feb;26(2):1811-1821. doi: 10.1007/s00784-021-04155-5. Epub 2021 Sep 7. Clin Oral Investig. 2022. PMID: 34491446 Free PMC article. Clinical Trial.
-
Microsurgical access flap and enamel matrix derivative for the treatment of periodontal intrabony defects: a controlled clinical study.J Clin Periodontol. 2003 Jun;30(6):496-504. doi: 10.1034/j.1600-051x.2003.00013.x. J Clin Periodontol. 2003. PMID: 12795787 Clinical Trial.
-
Minimally invasive non-surgical vs. surgical approach for periodontal intrabony defects: a randomised controlled trial.Trials. 2019 Jul 27;20(1):461. doi: 10.1186/s13063-019-3544-8. Trials. 2019. PMID: 31351492 Free PMC article.
-
Clinical effectiveness of anorganic bovine-derived hydroxyapatite matrix/cell-binding peptide grafts for regeneration of periodontal defects: a systematic review and meta-analysis.Regen Med. 2020 Dec;15(12):2379-2395. doi: 10.2217/rme-2020-0113. Epub 2020 Dec 24. Regen Med. 2020. PMID: 33356535
-
Clinical performance of minimally invasive periodontal surgery in the treatment of infrabony defects: Systematic review and meta-analysis.J Clin Periodontol. 2019 Dec;46(12):1236-1253. doi: 10.1111/jcpe.13201. Epub 2019 Oct 17. J Clin Periodontol. 2019. PMID: 31559646
Cited by
-
Matrix Metalloproteinase 9 (MMP-9) and Interleukin-8 (IL-8) in Gingival Crevicular Fluid after Minimally Invasive Periodontal Surgery with or without Er:YAG and Nd:YAG Laser Application.Antibiotics (Basel). 2024 Jul 27;13(8):704. doi: 10.3390/antibiotics13080704. Antibiotics (Basel). 2024. PMID: 39200004 Free PMC article.
-
Stem cell therapies for periodontal tissue regeneration: A meta-analysis of clinical trials.J Oral Biol Craniofac Res. 2023 Sep-Oct;13(5):589-597. doi: 10.1016/j.jobcr.2023.07.001. Epub 2023 Jul 31. J Oral Biol Craniofac Res. 2023. PMID: 37576801 Free PMC article.
-
Is periodontitis triggering an inflammatory response in the liver, and does this reaction entail oxidative stress?Odontology. 2025 Jul;113(3):889-902. doi: 10.1007/s10266-024-01032-x. Epub 2024 Dec 2. Odontology. 2025. PMID: 39621235 Review.
References
-
- Harrel SK. A minimally invasive surgical approach for periodontal regeneration: Surgical technique and observations. J Periodontol. 1999;70:1547–57. - PubMed
-
- Ghezzi C, Ferrantino L, Bernardini L, Lencioni M, Masiero S. Minimally invasive surgical technique in periodontal regeneration: A randomized controlled clinical trial pilot study. Int J Periodontics Restorative Dent. 2016;36:475–82. - PubMed
-
- Harrel SK. A minimally invasive surgical approach for periodontal bone grafting. Int J Periodontics Restorative Dent. 1998;18:161–9. - PubMed
-
- Sanz-Sánchez I, Montero E, Citterio F, Romano F, Molina A, Aimetti M. Efficacy of access flap procedures compared to subgingival debridement in the treatment of periodontitis. A systematic review and meta-analysis. J Clin Periodontol. 2020;47(Suppl 22):282–302. - PubMed
Publication types
LinkOut - more resources
Full Text Sources