Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2022;28(2):152-161.
doi: 10.5114/pedm.2022.116112.

Familial hypercholesterolemia - treatment update in children, systematic review

Sabina Ziółkowska  1 , Noëlle Kijek  1 , Iga Zendran  1 , Ewa Szuster  1 , Ewa Barg  2
Affiliations

Familial hypercholesterolemia - treatment update in children, systematic review

Sabina Ziółkowska et al. Pediatr Endocrinol Diabetes Metab. 2022.

Abstract
in English, Polish

Familial hypercholesterolaemia is one of the most common genetic diseases, and its first symptoms occur in childhood. Proper diagnosis and treatment prevent young patients from severe consequences in their future. The treatment of this dyslipidaemia is still evolving, and new promising agents are being discovered. In this review we summarize the old and new treatment methods of familial hypercholesterolaemia, giving an update estimated on the latest publications.

Rodzinna hipercholesterolemia jest jedną z najczęstszych chorób o podłożu genetycznym, a jej pierwsze objawy pojawiają się już w dzieciństwie. Właściwie postawiona diagnoza i leczenie może uchronić młodych pacjentów przed poważnymi konsekwencjami zdrowotnymi w przyszłości. Sposoby leczenia tej dyslipidemii ewoluują i pojawiają się nowe obiecujące leki. W pracy podsumowano już znane oraz nowe metody leczenia rodzinnej hipercholesterolemii, dokonując przeglądu najnowszej literatury.

Keywords: adolescents; children; cholesterol.; hyperlipoproteinaemia; hypercholesterolaemia.

PubMed Disclaimer

Conflict of interest statement

none declared.

Similar articles

See all similar articles

Cited by

References

    1. Expert Panel Integrated Guidelines for Cardiovascular Health and Risk Management: Summary Report. Pediatrics 2011; 128 (suppl. 5): 212–258. doi: 10.1542/peds.2009-2107C. - DOI - PMC - PubMed
    1. Ito MK, McGowan MP, Moriaty PM. Management of familial hyper-lipidemias in adult patients. Recommendations from National Lipid Association Expert Panel of Familial Hypercholesterolemia. J Clin Lipidol 2011: 5; 38–245. doi: 10.1016/j.jacl.2011.04.001. - DOI - PubMed
    1. National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III) final report. Circulation 2002; 106: 3143-3421. - PubMed
    1. De Ferranti SD, Newburge JW. Dyslipidemia in children and adolescents: Definition, screening, and diagnosis. UpToDate. https://www.uptodate.com/contents/dyslipidemia-in-children-and-adoles-ce... (Accessed 10.01.2022).
    1. Ribas SA, Santana da Silva LC. Anthropometric indices: predictors of dyslipidemia in children and adolescents from north of Brazil. Nutr Hosp 2012; 27: 1228–21235. doi: 10.3305/nh.2012.27.4.5798. - DOI - PubMed

Publication types

MeSH terms