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Review
. 2022 Aug;42(4):641-651.
doi: 10.19852/j.cnki.jtcm.2022.04.007.

Herbal anthelmintic agents: a narrative review

Manjusa Adak  1 , Pradeep Kumar  1
Affiliations
Review

Herbal anthelmintic agents: a narrative review

Manjusa Adak et al. J Tradit Chin Med. 2022 Aug.

Abstract

Helminths or Parasitic worms of humans may cause chronic and sometimes deadly diseases, considered as neglected tropical diseases (NTDs) that infect around two billion people worldwide. Plants have been used as anthelmintics from ancient times. This review is a compilation of plants as source of anthelmintic drug. All information presented in this review article regarding the anthelmintic activities of plants from 2005 and has been acquired by approaching various electronic databases, including Scopus, Google scholar, Web of science and PubMed. Literature was surveyed for anthelmintic activity of plants which showed that secondary metabolites of plants like terpenes, glycosides, saponins, flavonoids, tannins and alkaloids were having anthelmintic activity. Since this review is a compilation of anthelmintic activity of plants from the year 2005, it will definitely be a fruitful study for researchers working in this field.

Keywords: anthelmintics; biological products; helminthiasis; helminths.

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Figures

Figure 1
Figure 1. Secondary metabolites having anthelmintic activity
C50: lethal concentration 50.
Figure 2
Figure 2. Terpenes having anthelmintic activity
ED50: median effective dose; EC50: half maximal effective concentration.
Figure 3
Figure 3. Glycosides having anthelmintic activity (LC50 = 80.4 µM)
LC50: lethal concentration 50.
Figure 4
Figure 4. Saponins having anthelmintic activity
Figure 5
Figure 5. Flavonoids having anthelmintic activity
Figure 6
Figure 6. Tannins having anthelmintic activity
Figure 7
Figure 7. Alkaloids having anthelmintic activity
Figure 8
Figure 8. Non-protein amino acids having anthelmintic activity
Figure 9
Figure 9. Monophenols having anthelmintic activity
IC50: half maximal inhibitory concentration.
Figure 10
Figure 10. Benzene diols having anthelmintic activity
Figure 11
Figure 11. Substituted benzoic acids having anthelmintic activity
Figure 12
Figure 12. Cinnamic acid derivatives having anthelmintic activity
Figure 13
Figure 13. Prenyl derivatives having anthelmintic activity
Figure 14
Figure 14. Macrocyclic lactone having anthelmintic activity
Figure 15
Figure 15. Piperine and strychinine
See this image and copyright information in PMC

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