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. 2022 Sep 1;182(9):999-1000.
doi: 10.1001/jamainternmed.2022.2609.

Evaluation of a Best Practice Advisory on Ordering Prothrombin Time, International Normalized Ratio, and Partial Thromboplastin Time Tests

Madison Breeden  1 , Steven J Bernstein  1   2 , Rodney A Hayward  1   2 , A Mark Fendrick  1
Affiliations

Evaluation of a Best Practice Advisory on Ordering Prothrombin Time, International Normalized Ratio, and Partial Thromboplastin Time Tests

Madison Breeden et al. JAMA Intern Med. .

Abstract

This quality improvement study assesses changes in prothrombin time, international normalized ratio, and partial thromboplastin time testing after a best practices advisory was issued.

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Conflict of interest statement

Conflict of Interest Disclosures: Dr Bernstein reported receiving research funds from the Agency for Healthcare Research and Quality, US Department of Veterans Affairs, and Blue Cross Blue Shield of Michigan. Dr Hayward reported receiving research funds from the National Institutes of Health, US Department of Veterans Affairs, and UpToDate. Dr Hayward reported receiving a grant from the National Institute of Diabetes and Digestive and Kidney Dieases. Dr Fendrick reported serving as a consultant for AbbVie, Amgen, Bayer, Centivo, Community Oncology Association, Covered California, Eli Lilly and Company, EmblemHealth, Exact Sciences Corporation, Freedman HealthCare, GRAIL, Harvard University, Health & Wellness Innovations, Health at Scale Technologies, HealthCorum, Hygieia, Mallinckrodt Pharmaceuticals, MedZed, Merck & Co, Mercer, Montana Health CO-OP, Mother Goose Health, Pair Team, Phathom Pharmaceuticals, Sempre Health, SilverFern Health, State of Minnesota, Teladoc, US Department of Defense, Virginia Center for Health Innovation, Wellth, Wildflower Health, Yale New Haven Health System, and Zansors; reported receiving research support from the Agency for Healthcare Research and Quality, Boehringer Ingelheim, Gary and Mary West Health Policy Center, Arnold Ventures, the Laura and John Arnold Foundation, National Pharmaceutical Council, Patient-Centered Outcomes Research Institute, Pharmaceutical Research and Manufacturers of America, the Robert Wood Johnson Foundation, Michigan Department of Health and Human Services, and Centers for Medicare & Medicaid Services; and reported serving as coeditor of the American Journal of Managed Care, a member of the Medicare Evidence Development & Coverage Advisory Committee, and a partner in VBID Health. No other disclosures were reported.

Figures

Figure.
Figure.. Number of Prothrombin Time (PT), International Normalized Ratio (INR), and Partial Thromboplastin Time (PTT) Laboratory Tests Collected During the Study Period
Circles represent the tests ordered. The dotted line shows when the best practices advisory was instituted on May 15, 2021.
See this image and copyright information in PMC

References

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