Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2022 Sep:237:154026.
doi: 10.1016/j.prp.2022.154026. Epub 2022 Jul 13.

A review on the role of PRNCR1 in human disorders with an especial focus on cancer

Soudeh Ghafouri-Fard  1 , Tayyebeh Khoshbakht  2 , Bashdar Mahmud Hussen  3 , Aria Baniahmad  4 , Mohammad Taheri  5 , Alireza Salimi  6
Affiliations
Review

A review on the role of PRNCR1 in human disorders with an especial focus on cancer

Soudeh Ghafouri-Fard et al. Pathol Res Pract. 2022 Sep.

Abstract

Prostate Cancer Associated Non-Coding RNA 1 (PRNCR1) is a long non-coding RNA (lncRNA) which is transcribed from chromosome 8, plus strand. This lncRNA has been reported to be an oncogenic transcript participating in the pathogenesis of several kinds of cancers. Some single nucleotide polymorphisms within this lncRNA affect cancer risk. Moreover, few studies have revealed its possible roles in some non-neoplastic conditions, such as cisplatin-induced acute kidney injury, osteolysis after hip replacement, preeclampsia and pulmonary disorders. In the present narrative review, we explain diverse roles of PRNCR1 in human disorders.

Keywords: Biomarker; Cancer; Expression; LncRNA; PRNCR1.

PubMed Disclaimer

Conflict of interest statement

Competing Interest The authors declare they have no conflict of interest.

LinkOut - more resources