Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2022 Dec;33(12):2467-2478.
doi: 10.1007/s00198-022-06482-z. Epub 2022 Jul 18.

Gaps and alternative surgical and non-surgical approaches in the bone fragility management: an updated review

Umberto Tarantino  1   2 , Ida Cariati  1   3 , Chiara Greggi  1   3 , Riccardo Iundusi  2 , Elena Gasbarra  2 , Giovanni Iolascon  4 , Andreas Kurth  5 , Kristina E Akesson  6 , Mary Bouxsein  7 , Paolo Tranquilli Leali  8 , Roberto Civinini  9 , Francesco Falez  10 , Maria Luisa Brandi  11
Affiliations
Review

Gaps and alternative surgical and non-surgical approaches in the bone fragility management: an updated review

Umberto Tarantino et al. Osteoporos Int. 2022 Dec.

Abstract

Osteoporotic fractures are one of the major problems facing healthcare systems worldwide. Undoubtedly, fragility fractures of the hip represent a far greater burden in terms of morbidity, mortality, and healthcare costs than other fracture sites. However, despite the significant impact on the health and quality of life of older adults, there is a general lack of awareness of osteoporosis, which results in suboptimal care. In fact, most high-risk individuals are never identified and do not receive adequate treatment, leading to further fragility fractures and worsening health status. Furthermore, considering the substantial treatment gap and the proven cost-effectiveness of fracture prevention programs such as Fracture Liaison Services, urgent action is needed to ensure that all individuals at high risk of fragility fracture are adequately assessed and treated. Based on this evidence, the aim of our review was to (i) provide an overview and comparison of the burden and management of fragility fractures, highlighting the main gaps, and (ii) highlight the importance of using alternative approaches, both surgical and non-surgical, with the aim of implementing early prevention of osteoporotic fractures and improving the management of osteoporotic patients at imminent and/or very high risk of fracture.

Keywords: Fracture; Fracture risk; Fragility; Gaps, Osteoporosis; Osteoporosis management.

PubMed Disclaimer

References

    1. Tarantino U, Iolascon G, Cianferotti L et al (2017) Clinical guidelines for the prevention and treatment of osteoporosis: summary statements and recommendations from the Italian Society for Orthopaedics and Traumatology. J Orthop Traumatol Off J Ital Soc Orthop Traumatol 18:3–36. https://doi.org/10.1007/s10195-017-0474-7 - DOI
    1. Nuti R, Brandi ML, Checchia G et al (2019) Guidelines for the management of osteoporosis and fragility fractures. Intern Emerg Med 14:85–102. https://doi.org/10.1007/s11739-018-1874-2 - DOI - PubMed
    1. Wolf-Maier K, Cooper RS, Banegas JR et al (2003) Hypertension prevalence and blood pressure levels in 6 European countries, Canada, and the United States. JAMA 289:2363–2369. https://doi.org/10.1001/jama.289.18.2363 - DOI - PubMed
    1. Kanis JA, Johnell O, Oden A et al (2000) Long-term risk of osteoporotic fracture in Malmö. Osteoporos Int J Establ Result Coop Between Eur Found Osteoporos Natl Osteoporos Found USA 11:669–674. https://doi.org/10.1007/s001980070064 - DOI
    1. Kanis JA, Odén A, McCloskey EV et al (2012) A systematic review of hip fracture incidence and probability of fracture worldwide. Osteoporos Int a J Establ Result Coop Between Eur Found Osteoporos Natl Osteoporos Found USA 23:2239–2256. https://doi.org/10.1007/s00198-012-1964-3 - DOI

Substances

LinkOut - more resources