Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2022 Oct;58(10):1836-1840.
doi: 10.1111/jpc.16120. Epub 2022 Jul 19.

'Long COVID': Symptom persistence in children hospitalised for COVID-19

Affiliations

'Long COVID': Symptom persistence in children hospitalised for COVID-19

Ali A Asadi-Pooya et al. J Paediatr Child Health. 2022 Oct.

Abstract

Aim: We aimed to describe the long-term outcome with respect to symptom persistence amongst children hospitalised for COVID-19.

Methods: This was a follow-up study of 58 children and adolescents hospitalised with COVID-19. For all patients, the data were collected in a phone call to the family in December 2021 (9 months after the initial study and more than 13 months after their admission to hospital). We inquired about their current health status and obtained information, if the responding parent consented orally to participate and answer the questions.

Results: Fifty-one children and adolescents were studied. Only five patients (10%) had persistent symptoms compatible with long-COVID; the reported symptoms include fatigue in four (8%), weakness in three (6%), exercise intolerance in two (4%) and shortness of breath in two (4%) patients. Four patients (7.8%), who did not have any symptoms of long-COVID in phase 1 of the study, reported new-onset symptoms or complaints that are potentially compatible with the diagnosis of long-COVID (weakness, myalgia, excess sputum, cough, fatigue) in the current phase.

Conclusions: Symptom persistence of long-COVID is infrequent amongst children hospitalised for COVID-19. Most of the symptoms of long-COVID will resolve with the passage of time and the residual symptoms are often mild and tolerable. The scientific community should carefully and clearly define long-COVID and its natural course in order to facilitate and harmonise future studies.

Keywords: COVID-19; chronic; coronavirus; paediatrics.

PubMed Disclaimer

References

    1. Sudre CH, Murray B, Varsavsky T et al. Attributes and predictors of long COVID. Nat. Med. 2021; 27: 626–31. - PMC - PubMed
    1. Sykes DL, Holdsworth L, Jawad N, Gunasekera P, Morice AH, Crooks MG. Post‐COVID‐19 symptom burden: What is long‐COVID and how should we manage it? Lung 2021; 199: 113–9. - PMC - PubMed
    1. Jacobson KB, Rao M, Bonilla H et al. Patients with uncomplicated COVID‐19 have long‐term persistent symptoms and functional impairment similar to patients with severe COVID‐19: A cautionary tale during a global pandemic. Clin. Infect. Dis. 2021; 73: e826–9. - PMC - PubMed
    1. Asadi‐Pooya AA, Akbari A, Emami A et al. Risk factors associated with long COVID syndrome: A retrospective study. Iran J. Med. Sci. 2021; 46: 428–36. - PMC - PubMed
    1. Guedj E, Campion JY, Dudouet P et al. 18F‐FDG brain PET hypometabolism in patients with long COVID. Eur. J. Nucl. Med. Mol. Imaging 2021; 48: 2823–33. - PMC - PubMed