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. 2022 Feb 28;64(1):7-12.
doi: 10.3897/folmed.64.e59297.

Lysophospholipid Metabolism and Signalling in Non-Alcoholic Fatty Liver Disease

Charalambos Papadopoulos  1 , Ioannis Tentes  1 , Dimitrios Papazoglou  1 , Konstantinos Anagnostopoulos  1
Affiliations

Lysophospholipid Metabolism and Signalling in Non-Alcoholic Fatty Liver Disease

Charalambos Papadopoulos et al. Folia Med (Plovdiv). .

Abstract

Non-alcoholic liver disease (NAFLD) constitutes a global health pandemic. It is estimated that about 25% of the world's population suffers from NAFLD. In the long-term, a subgroup of the patients can develop inflammation and fibrosis. The end result in some cases is cirrhosis and even liver-related death. The epidemiology and natural history of NAFLD lead to extreme financial costs.

Keywords: non-alcoholic fatty liver disease lysophosphatidylcholine lysophosphatidic acid lysophospholipids sphingosine 1-phosphate.

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