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Review

Intraoperative BOLD-fMRI Cerebrovascular Reactivity Assessment

Giovanni Muscas  1   2   3 , Christiaan Hendrik Bas van Niftrik  1   3 , Martina Sebök  1   3 , Giuseppe Esposito  1   3 , Luca Regli  1   3 , Jorn Fierstra  1   3
Giuseppe Esposito  1 , Luca Regli  1 , Marco Cenzato  2 , Yasuhiko Kaku  3 , Michihiro Tanaka  4 , Tetsuya Tsukahara  5
, editors.
In: Trends in Cerebrovascular Surgery and Interventions [Internet]. Cham (CH): Springer; 2021.
.
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Review

Intraoperative BOLD-fMRI Cerebrovascular Reactivity Assessment

Giovanni Muscas et al.
Free Books & Documents

Excerpt

Blood oxygenation-level dependent cerebrovascular reactivity (BOLD-CVR) has gained attention in recent years as an effective way to investigate CVR, a measure of the hemodynamic state of the brain, with high spatial and temporal resolution. An association between impaired CVR and diverse pathologies has been observed, especially in ischemic cerebrovascular diseases and brain gliomas. The ability to obtain this information intraoperatively is novel and has not been widely tested. We report our first experience with this intraoperative technique in vascular and oncologic neurosurgical patients, discuss the results of its feasibility, and the possible developments of the intraoperative employment of BOLD-CVR.

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References

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