Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2022 Jun 28:11:2022-2-3.
doi: 10.7573/dic.2022-2-3. eCollection 2022.

Tackling the clinical complexity of breast cancer

Marco Vincenzo Lenti  1 , Federico Sottotetti  2 , Gino Roberto Corazza  1
Affiliations

Tackling the clinical complexity of breast cancer

Marco Vincenzo Lenti et al. Drugs Context. .

Abstract

Clinical complexity (CC) is an increasingly recognized feature of internal medicine patients who are often characterized by complex needs determined by both biological (i.e. intrinsic to the patient or disease biology) and non-biological (i.e. socioeconomic, cultural, environmental, behavioural) factors. Breast cancer, one of the most common malignancies worldwide, certainly represents an example of a complex disease. Nonetheless, the concept itself of CC and its possible determinants in breast cancer have been poorly addressed. We herein provide our view about the possible factors triggering CC, the key issues of CC and the related unmet needs in breast cancer.

Keywords: cancer; internal medicine; multimorbidity; oncology.

PubMed Disclaimer

Conflict of interest statement

Disclosure and potential conflicts of interest: The authors report no conflicts of interest. The authors alone are responsible for the content and writing of this article. The International Committee of Medical Journal Editors (ICMJE) Potential Conflicts of Interests form for the authors is available for download at: https://www.drugsincontext.com/wp-content/uploads/2022/05/dic.2022-2-3-COI.pdf

Similar articles

See all similar articles

Cited by

References

    1. Corazza GR, Formagnana P, Lenti MV. Bringing complexity into clinical practice: an internistic approach. Eur J Intern Med. 2019;61:9–14. doi: 10.1016/j.ejim.2018.11.009. - DOI - PubMed
    1. Plsek PE, Greenhalgh T. The challenge of complexity in health care. BMJ. 2001;323:625–628. doi: 10.1136/bmj.323.7313.625. - DOI - PMC - PubMed
    1. Wilson T, Holt T, Greenhalgh T. Complexity science: complexity and clinical care. BMJ. 2001;323:685–688. doi: 10.1136/bmj.323.7314.685. - DOI - PMC - PubMed
    1. Safford MM. The complexity of complex patients. J Gen Intern Med. 2015;30:1724–1725. doi: 10.1007/s11606-015-3472-6. - DOI - PMC - PubMed
    1. Hong CS, Atlas SJ, Ashburner JM, et al. Evaluating a model to predict primary care physician-defined complexity in a large academic primary care practice-based research network. J Gen Intern Med. 2015;30:1741–1747. doi: 10.1007/s11606-015-3357-8. - DOI - PMC - PubMed