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Editorial
. 2022 Jul 19;14(14):5617-5619.
doi: 10.18632/aging.204192. Epub 2022 Jul 19.

Restoring rhythm to prevent age-related fractures

Annelies E Smit  1 , Maaike Schilperoort  2 , Elizabeth M Winter  1
Affiliations
Editorial

Restoring rhythm to prevent age-related fractures

Annelies E Smit et al. Aging (Albany NY). .
No abstract available

Keywords: chronotherapy; circadian rhythm; fractures; glucocorticoids; osteoporosis.

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Figures

Figure 1
Figure 1
Bone health depends on diurnal variation in bone turnover, which is regulated by the circadian timing system. (A) With aging circadian rhythmicity is disturbed, which may contribute to osteoporosis (B). SCN= Suprachiasmatic nucleus, GC= glucocorticoid, HPA axis= hypothalamic-pituitary-adrenal axis. Figure created with BioRender.com
See this image and copyright information in PMC

References

    1. Schilperoort M, et al. FASEB J. 2020; 34:1052–64. 10.1096/fj.201901929R - DOI - PubMed
    1. Winter EM, et al. JBMR Plus. 2021; 5:e10504. 10.1002/jbm4.10504 - DOI - PMC - PubMed
    1. Fujihara Y, et al. Bone. 2014; 61:1–9. 10.1016/j.bone.2013.12.026 - DOI - PubMed
    1. Schilperoort M, et al. Aging Cell. 2021; 20:e13474. 10.1111/acel.13474 - DOI - PMC - PubMed
    1. Nakamura TJ, et al. J Physiol Sci. 2016; 66:367–74. 10.1007/s12576-016-0439-2 - DOI - PMC - PubMed

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