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. 1987 May;23(3):233-8.
doi: 10.1099/00222615-23-3-233.

Interaction of Campylobacter pyloridis with human immune defence mechanisms

H Pruul, P C Lee, C S Goodwin, P J McDonald

Interaction of Campylobacter pyloridis with human immune defence mechanisms

H Pruul et al. J Med Microbiol. 1987 May.

Abstract

The in-vitro susceptibility to host immune defence mechanisms of Campylobacter pyloridis was investigated. C. pyloridis was sensitive to antibody-dependent complement-mediated bactericidal activity of serum. The bacteria were phagocytosed and efficiently killed by polymorphonuclear neutrophils in the presence of serum opsonins. Serum opsonin depletion studies indicated that an intact classical complement pathway was required for optimal phagocytic killing.

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