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. 2022 Jun 7;9(7):ofac282.
doi: 10.1093/ofid/ofac282. eCollection 2022 Jul.

Real-world Experience of Sotrovimab in High-risk, Immunocompromised COVID-19 Patients

Navina K Birk  1 , Saniya Jain  1 , Louis Massoud  1 , Diya Ramesh  1 , Lea Monday  1 , Bruce Muma  1 , Jonathan Williams  1 , George Alangaden  1 , Mayur Ramesh  1
Affiliations
Free PMC article

Real-world Experience of Sotrovimab in High-risk, Immunocompromised COVID-19 Patients

Navina K Birk et al. Open Forum Infect Dis. .
Free PMC article

Abstract

We completed a real-world analysis of 498 consecutive high-risk nonimmunocompromised and immunocompromised patients who received sotrovimab during the B.1.1.529 surge. Emergency department visits/hospitalizations and 30-day all-cause mortality between the 2 groups were similar. When administered early, sotrovimab is effective at preventing coronavirus disease 2019 progression in immunocompromised and nonimmunocompromised patients.

Keywords: COVID-19; immunocompromised hosts; monoclonal antibody; outcomes; sotrovimab.

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