Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2022 Jun 17:79:104009.
doi: 10.1016/j.amsu.2022.104009. eCollection 2022 Jul.

MDR-TB in Pakistan: Challenges, efforts, and recommendations

Affiliations

MDR-TB in Pakistan: Challenges, efforts, and recommendations

Mahad Ahmed Khan et al. Ann Med Surg (Lond). .

Abstract

Tuberculosis (TB), a global health concern is also a leading cause of mortality and morbidity across Pakistan affecting a major proportion of the population. The absence of an integrated system to control the spread of TB has led to a rise in multidrug resistant strains of TB (MDR-Tb) which do not exhibit any sensitivity towards the first line therapy for TB. Such adverse circumstances call for effective planning strategies to mitigate the health hazards of MDR-TB. This article briefly highlights the challenges encountered by the already burdened healthcare system and suggests relatively inexpensive approaches to tackle the ongoing crisis associated with MDR-TB on a national scale.

Keywords: COVID-19; MDR, multiple drug resistance; MDR-TB; PMDT, Programmatic Management of Drug-Resistant Tuberculosis; Pakistan; Tuberculosis.

PubMed Disclaimer

Conflict of interest statement

None.

Similar articles

Cited by

References

    1. Aftab A., Afzal S., Qamar Z., Idrees M. Early detection of MDR Mycobacterium tuberculosis mutations in Pakistan. Sci Reports 2021 111. 2021;11(1):1–5. doi: 10.1038/s41598-021-96116-x. - DOI - PMC - PubMed
    1. Ullah I., Javaid A., Tahir Z., et al. Pattern of drug resistance and risk factors associated with development of drug resistant Mycobacterium tuberculosis in Pakistan. PLoS One. 2016;11(1) doi: 10.1371/JOURNAL.PONE.0147529. - DOI - PMC - PubMed
    1. Ali S., Khan M.T., Khan A.S., et al. Prevalence of multi-drug resistant Mycobacterium tuberculosis in Khyber Pakhtunkhwa – a high tuberculosis endemic area of Pakistan. Pol. J. Microbiol. 2020;69(2):133. doi: 10.33073/PJM-2020-005. - DOI - PMC - PubMed
    1. Sattar A., Biomed S., Sci J., Res T., Review M. Rising trends of multidrug resistant (MDR)tuberculosis in Pakistan. Biomed J Sci Tech Res. 2018;12(3):1–4. doi: 10.26717/BJSTR.2018.12.002254. - DOI
    1. Ahmad N., Javaid A., Sulaiman S.A.S., Ming L.C., Ahmad I., Khan A.H. Resistance patterns, prevalence, and predictors of fluoroquinolones resistance in multidrug resistant tuberculosis patients. Braz. J. Infect. Dis. 2016;20(1):41–47. doi: 10.1016/J.BJID.2015.09.011. - DOI - PMC - PubMed