Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2022 Jul-Aug;19(4):14791641221113788.
doi: 10.1177/14791641221113788.

Impact of diabetes on long-term all-cause re-hospitalization after revascularization with percutaneous coronary intervention

Kirstine N Hansen  1 , Manijeh Noori  1 , Evald H Christiansen  2 , Eskild B Kristiansen  3 , Michael Maeng  2 , Ann Dorthe O Zwisler  1 , Britt Borregaard  1 , Rikke Søgaard  4 , Karsten T Veien  1 , Anders Junker  1 , Lisette Okkels Jensen  1
Affiliations

Impact of diabetes on long-term all-cause re-hospitalization after revascularization with percutaneous coronary intervention

Kirstine N Hansen et al. Diab Vasc Dis Res. 2022 Jul-Aug.

Abstract

Purpose: The purpose of the study was to investigate the incidence, cause and probability of re-hospitalization within 30 and 365 days after percutaneous coronary intervention (PCI) in patients with diabetes.

Method: Between January 2010 and September 2014, 2763 patients with diabetes were treated with PCI at two Hospitals in Western Denmark. Reasons for readmission within 30 and 365 days were identified.

Results: Readmission risks for patients with diabetes were 58% within 365 days and 18% within 30 days. Reason for readmission was ischemic heart disease (IHD) in 725 patients (27%), and non-IHD-related reasons in 826 patients (31%). IHD-related readmission within 365 days was associated with female gender (OR 1.3, 95% CI: 1.1-1.5), and non-ST-segment elevation myocardial infarction, compared to stable angina at the index hospitalization (OR 1.3, 95% CI: 1.1-1.6). Among patients with diabetes, increased risk of readmission due to other reasons were age (OR 1.3, 95% CI: 1.2-1.5) and higher scores of modified Charlson Comorbidity index (CCI): CCI ≥3 (OR 3.6, 95% CI: 2.8-4.6).

Conclusion: More than half of the patients with diabetes mellitus undergoing PCI were readmitted within 1 year. Comorbidities were the strongest predictor for non-IHD-related readmission, but did not increase the risk for IHD-related readmissions.

Keywords: Coronary artery disease; diabetes mellitus; percutaneous coronary intervention; re-hospitalization.

PubMed Disclaimer

Conflict of interest statement

Declaration of conflicting interests: The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

Figures

Figure 1.
Figure 1.
Kaplan-Meier cumulative event curves with 95% confidence limits for probability of readmission after PCI within a year as per various factors. (a) Gender. (b) modified Charlson comorbidity index. (c) Indication for percutaneous coronary intervention.
See this image and copyright information in PMC

References

    1. Orbach A, Halon DA, Jaffe R, et al. Impact of diabetes and early revascularization on the need for late and repeat procedures. Cardiovasc Diabetol 2018; 17: 25. - PMC - PubMed
    1. Ida S, Kaneko R, Imataka K, et al. Relationship between frailty and mortality, hospitalization, and cardiovascular diseases in diabetes: a systematic review and meta-analysis. Cardiovasc Diabetol 2019; 18: 81. - PMC - PubMed
    1. Einarson TR, Acs A, Ludwig C, et al. Psrevalence of cardiovascular disease in type 2 diabetes: a systematic literature review of scientific evidence from across the world in 2007-2017. Cardiovasc Diabetol 2018; 17: 83. - PMC - PubMed
    1. Montalescot G, Sechtem U, Achenbach S, et al. ESC guidelines on the management of stable coronary artery disease: the task force on the management of stable coronary artery disease of the European Society of Cardiology. Eur Heart J 2013; 34: 2949–3003. - PubMed
    1. Maeng M, Jensen LO, Kaltoft A, et al. Comparison of stent thrombosis, myocardial infarction, and mortality following drug-eluting versus bare-metal stent coronary intervention in patients with diabetes mellitus. Am J Cardiol 2008; 102: 165–172. - PubMed