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. 2022 Jul 30:12:04041.
doi: 10.7189/jogh.12.04041.

The burden of alcoholic cardiomyopathy in China and different regions around the world

Jing Zhang #  1   2   3 , Hailing Liu #  4 , Xiang Bu  5 , Qun Lu  1   2   3 , Lu Cheng  6 , Aiqun Ma  1   2   3 , Tingzhong Wang  1   2   3
Affiliations

The burden of alcoholic cardiomyopathy in China and different regions around the world

Jing Zhang et al. J Glob Health. .

Abstract

Background: Alcoholic cardiomyopathy (ACM) remains a significant public health issue with a growing global burden. The burden of ACM in China and different regions remains poorly understood.

Methods: Data on ACM deaths, disability-adjusted life years (DALYs), the corresponding global age-standardized death rate (ASDR), age-standardized DALY rate and estimated annual percentage change (EAPC) were analysed based on age, sex, socio-demographic index (SDI) quintiles, different regions and in China from the Global Burden of Disease (GBD) study 2019.

Results: Globally, the death rate and DALYs due to ACM were 71 723 and 2 441 108 in 2019, 33.06% and 38.79% increase from 1990, respectively. The corresponding ASDR and age-standardized DALY rate decreased with EAPC of -1.52 (95% uncertainty interval (UI) = -2.39, -0.65) and -1.12 (95% UI = -2.14, -0.10). The high-middle SDI regions, especially Eastern Europe, showed the highest number of ACM-related deaths and DALYs. The ACM-related deaths and DALYs were 2545 and 87823 in China in 2019, 171.03% and 147.17% increase from 1990, respectively. Unlike the world level, ASDR and age-standardized DALY rate also increased in China. The ACM burden is higher in men, and people with 50 to 69 years old accounted for the most.

Conclusions: ACM burden in China and across the world increased substantially from 1990 to 2019. The greatest burden was borne by the high-middle SDI regions, especially by men aged 50-69 years old. Geographically and gender-age tailored strategies were needed to prevent ACM.

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Conflict of interest statement

Competing interests: The authors completed the ICMJE Declaration of Interest Form (available upon request from the corresponding author), and declare no conflicts of interest.

Figures

Figure 1
Figure 1
The global deaths burden of ACM in 204 countries and territories. Panel A. The absolute number of ACM death cases in 2019; Panel B. The ASDR (per 100 000 persons) of ACM in 2019. Panel C. The EAPC of ACM ASDRs between 1990 and 2019. ACM – alcoholic cardiomyopathy, ASDR – age standardized death rate, EAPC – estimated annual percentage change.
Figure 2
Figure 2
The global ACM burden in both sexes and different age groups in 2019. Panel A. The absolute number of global death cases. Panel B. The absolute number of global DALYs. Panel C. The absolute number of death cases in China. Panel D. The absolute number of DALYs in China. ACM – alcoholic cardiomyopathy, DALY – disability-adjusted life year.
Figure 3
Figure 3
The proportion of the three age groups (15-49 years, 50-69 years and 70+ years) for ACM deaths (Panel A) and DALYs (Panel B) globally and in five SDI quintiles between 1990 and 2019. ACM – alcoholic cardiomyopathy, SDI – socio-demographic index, DALY – disability-adjusted life year.
Figure 4
Figure 4
The change trends of ASDR, age-standardized DALY rate globally and among different SDI quintiles between 1990 and 2019. Panel A. ASDR; Panel B. age standardized DALY rate. SDI – socio-demographic index, ASDR – age-standardized death rate, DALY – disability-adjusted life year.
Figure 5
Figure 5
Trends of ASDR and age-standardized DALY rate of ACM in 21 GBD regions from 1990 to 2019. Panel A. The ASDR of ACM. Panel B. age-standardized DALY rate of ACM. ACM – alcoholic cardiomyopathy, GBD – global burden of diseases, SDI – social-demographic index, ASDR – age-standardized death rate, DALY – disability-adjusted life year.
Figure 6
Figure 6
The change trends of ASDR, age-standardized DALY rate in China between 1990 and 2019. Panel A. ASDR. Panel B. age standardized DALY rate. ASDR – age-standardized death rate, DALY – disability-adjusted life year.
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