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. 2022 Dec;187(6):1011-1013.
doi: 10.1111/bjd.21782. Epub 2022 Aug 12.

Cutaneous manifestations of lymphoid-variant hypereosinophilic syndrome

Affiliations

Cutaneous manifestations of lymphoid-variant hypereosinophilic syndrome

Claire Laurent et al. Br J Dermatol. 2022 Dec.

Abstract

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Figures

Figure 1
Figure 1
Clinical characteristics of skin involvement in lymphoid‐variant hypereosinophilic syndrome and associated cutaneous T‐cell lymphoma. (a) Clinical manifestations of lymphoid‐variant hypereosinophilic syndrome. Erythematous papules of the neck (upper left) and eczema‐like lesions, predominating in the folds (upper middle image). (b–d) Clinical characteristics of CD3 CD4+ T‐cell lymphoproliferative hypereosinophilic syndrome associated with cutaneous T‐cell lymphoma. (b) Hypopigmented macules on the foot in a patient with associated stage IA mycosis fungoides. (c) Erythematous infiltrated papules in a patient with primary cutaneous peripheral T‐cell lymphoma not otherwise specified (lower left) and erythroderma in a patient with stage III mycosis fungoides (lower middle image). (d) Erythematous, lax plaques of the axillary fold in a patient with a diagnosis of stage I mycosis fungoides.

References

    1. Valent P, Klion AD, Horny HP et al. Contemporary consensus proposal on criteria and classification of eosinophilic disorders and related syndromes. J Allergy Clin Immunol 2012; 130:607–12. - PMC - PubMed
    1. Lefèvre G, Copin MC, Roumier C et al. CD3− CD4+ lymphoid variant of hypereosinophilic syndrome: nodal and extranodal histopathological and immunophenotypic features of a peripheral indolent clonal T‐cell lymphoproliferative disorder. Haematologica 2015; 100:1086–95. - PMC - PubMed
    1. Lefèvre G, Copin MC, Staumont‐Sallé D et al. The lymphoid variant of hypereosinophilic syndrome: study of 21 patients with CD3− CD4+ aberrant T‐cell phenotype. Medicine (Baltimore) 2014; 93:255–66. - PMC - PubMed
    1. Shi Y, Wang C. What we have learned about lymphocytic variant hypereosinophilic syndrome: a systematic literature review. Clin Immunol 2022; 237:108982. - PubMed
    1. Simon HU, Plötz SG, Dummer R, Blaser K. Abnormal clones of T cells producing interleukin‐5 in idiopathic eosinophilia. N Engl J Med 1999; 341:1112–20. - PubMed