Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Editorial
. 2022 Jul 26;80(4):329-331.
doi: 10.1016/j.jacc.2022.04.061.

Blood Hyperviscosity: A Novel Link Between Hyperinflammation and Hypercoagulability in COVID-19

Affiliations
Editorial

Blood Hyperviscosity: A Novel Link Between Hyperinflammation and Hypercoagulability in COVID-19

Aldo Bonaventura et al. J Am Coll Cardiol. .
No abstract available

Keywords: COVID-19; SARS-CoV-2; blood viscosity; coagulation; immunothrombosis; inflammation; thrombosis.

PubMed Disclaimer

Conflict of interest statement

Funding Support and Author Disclosures Dr Bonaventura has received a travel grant from Kiniksa Pharmaceuticals Ltd to attend the 2019 American Heart Association Scientific Sessions; and has recevied honoraria from Effetti s.r.l. (Milan, Italy) to collaborate on a medical website Inflammology. Dr Potere has received a training fellowship from the International Society on Thrombosis and Haemostasis.

Figures

None
Graphical abstract

Comment on

References

    1. Lamers M.M., Haagmans B.L. SARS-CoV-2 pathogenesis. Nat Rev Microbiol. 2022;20:270–284. - PubMed
    1. Engelmann B., Massberg S. Thrombosis as an intravascular effector of innate immunity. Nat Rev Immunol. 2013;13:34–45. - PubMed
    1. Bonaventura A., Vecchie A., Dagna L., et al. Endothelial dysfunction and immunothrombosis as key pathogenic mechanisms in COVID-19. Nat Rev Immunol. 2021;21:319–329. - PMC - PubMed
    1. Merrill J.T., Erkan D., Winakur J., James J.A. Emerging evidence of a COVID-19 thrombotic syndrome has treatment implications. Nat Rev Rheumatol. 2020;16:581–589. - PMC - PubMed
    1. Panigada M., Bottino N., Tagliabue P., et al. Hypercoagulability of COVID-19 patients in intensive care unit: A report of thromboelastography findings and other parameters of hemostasis. J Thromb Haemost. 2020;18:1738–1742. - PMC - PubMed