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Review
. 2022 Jul 21:practneurol-2022-003370.
doi: 10.1136/practneurol-2022-003370. Online ahead of print.

Multiple sclerosis and the risk of infection: Association of British Neurologists consensus guideline

Marija Cauchi  1 , Mark Willis  2 , Angela Andrews  3 , Matthijs Backx  4 , Wallace Brownlee  5 , Helen L Ford  6 , Bruno Gran  7   8 , Stephen Jolles  9 , Sian Price  10 , Waqar Rashid  11 , Klaus Schmierer  12   13 , Emma C Tallantyre  2
Affiliations
Review

Multiple sclerosis and the risk of infection: Association of British Neurologists consensus guideline

Marija Cauchi et al. Pract Neurol. .

Abstract

Infection in people with multiple sclerosis (MS) is of major concern, particularly for those receiving disease-modifying therapies. This article explores the risk of infection in people with MS and provides guidance-developed by Delphi consensus by specialists involved in their management-on how to screen for, prevent and manage infection in this population.

Keywords: infectious diseases; multiple sclerosis.

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Conflict of interest statement

Competing interests: WB has received honoraria from Biogen, Celgene, Merck, Mylan, Novartis, Roche and Sanofi. HLF has received support from the Health Technology Assessment Programme (NIHR) and the UK MS Society. In the past 3 years, HLF has been a local principal investigator for trials in MS funded by Novartis, Roche and Biogen Idec and has taken part in advisory boards and consultancy for Merck, Teva, Biogen, and Novartis. SJ reports Advisory Board, Speaker, Conference, Drug Safety Monitoring Board, and project support from CSL Behring, Takeda, BioCryst Pharmaceuticals, Swedish Orphan Biovitrum, Biotest, Binding Site, LFB, Octapharma, Grifols, UCB Pharma, Sanofi, Pharming, Weatherden and Zarodex Therapeutics Limited. SJ is a member of the IPOPI SAFE Taskforce and COVIC19 Trial Group. BG has received personal compensation for consultancy from Merck, Roche, Biogen, Teva UK, and GW Pharma. He has received unrestricted research grants from Biogen Idec, Merck, Bayer Healthcare, Teva UK, Novartis, and Genzyme; and support for the attendance of clinical and research conferences from Biogen, Merck, Bayer Healthcare, Teva UK, Novartis, Genzyme, and CelGene. KS has received research support from Biogen, Merck KGaA, and Novartis, speaking honoraria from, and/or served in an advisory role for, Amgen, Biogen, EMD Serono, Merck KGaA, Novartis, Roche, Sanofi-Genzyme, and Teva; and remuneration for teaching activities from AcadeMe, Medscape and the Neurology Academy.

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