Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2022 Jul 5:13:936948.
doi: 10.3389/fendo.2022.936948. eCollection 2022.

Associations Between Asthma and Polycystic Ovary Syndrome: Current Perspectives

Yue Xu  1 , Zhi-Yang Zhou  1 , Jie-Xue Pan  1 , He-Feng Huang  1   2   3
Affiliations
Review

Associations Between Asthma and Polycystic Ovary Syndrome: Current Perspectives

Yue Xu et al. Front Endocrinol (Lausanne). .

Abstract

A potential correlation between polycystic ovary syndrome (PCOS) and asthma, used to be identified as diseases originating from two independent systems, has been supported by increasing evidence. From an epidemiological perspective, mounting studies have confirmed that women suffering from PCOS exhibit increased susceptibility to asthma. Meanwhile, PCOS and asthma seem to share several mutual pathological conditions, such as metabolic disorders, hormonal fluctuation, proinflammatory state, etc. Here, we further elucidate the correlation between asthma and PCOS by focusing on the internal common pathophysiology and adverse influences on women's health. Understanding the internal connection between PCOS and asthma may shed light on developing new prevention and control strategies to fight against these conditions.

Keywords: asthma; chronic inflammation; metabolic syndrome; polycystic ovary syndrome; reproductive health.

PubMed Disclaimer

Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Figures

Figure 1
Figure 1
Potential associations between PCOS and asthma. Women with PCOS or asthma are characterized by several common disease phenotypes, including metabolic syndrome, irregular menstruation, impaired fertility and mood disturbances. And chronic local and systemic inflammation may act as one of the common molecular mechanisms behind these phenomena. Image was created with Biorender®.
See this image and copyright information in PMC

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. Bozdag G, Mumusoglu S, Zengin D, Karabulut E, Yildiz BO. The Prevalence and Phenotypic Features of Polycystic Ovary Syndrome: A Systematic Review and Meta-Analysis. Hum Reprod Oxf Engl (2016) 31(12):2841–55. doi: 10.1093/humrep/dew218 - DOI - PubMed
    1. Sirmans SM, Pate KA. Epidemiology, Diagnosis, and Management of Polycystic Ovary Syndrome. Clin Epidemiol (2013) 6:1–13. doi: 10.2147/CLEP.S37559 - DOI - PMC - PubMed
    1. Rotterdam ESHRE/ASRM-Sponsored PCOS Consensus Workshop Group . Revised 2003 Consensus on Diagnostic Criteria and Long-Term Health Risks Related to Polycystic Ovary Syndrome. Fertil Steril (2004) 81(1):19–25. doi: 10.1016/j.fertnstert.2003.10.004 - DOI - PubMed
    1. Doherty DA, Newnham JP, Bower C, Hart R. Implications of Polycystic Ovary Syndrome for Pregnancy and for the Health of Offspring. Obstet Gynecol (2015) 125(6):1397–406. doi: 10.1097/AOG.0000000000000852 - DOI - PubMed
    1. Ollila MME, Piltonen T, Puukka K, Ruokonen A, Järvelin MR, Tapanainen JS, et al. . Weight Gain and Dyslipidemia in Early Adulthood Associate With Polycystic Ovary Syndrome: Prospective Cohort Study. J Clin Endocrinol Metab (2016) 101(2):739–47. doi: 10.1210/jc.2015-3543 - DOI - PubMed

Publication types