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. 2022 Jun 15;9(7):ofac288.
doi: 10.1093/ofid/ofac288. eCollection 2022 Jul.

Decreased Risk of Coronavirus Disease 2019-Related Hospitalization Associated With the Omicron Variant of Severe Acute Respiratory Syndrome Coronavirus 2

Jessica P Ridgway  1 , Samuel Tideman  2 , Bill Wright  2 , Ari Robicsek  2
Affiliations

Decreased Risk of Coronavirus Disease 2019-Related Hospitalization Associated With the Omicron Variant of Severe Acute Respiratory Syndrome Coronavirus 2

Jessica P Ridgway et al. Open Forum Infect Dis. .

Abstract

Among 134 223 patients with coronavirus disease 2019 (COVID-19), we assessed how risk of hospitalization changed at different intervals in the pandemic, controlling for prior COVID-19 immunity. In multivariable analysis, outpatients with COVID-19 during the Omicron-predominant time period had significantly lower odds of hospitalization compared to pre-Delta (adjusted odds ratio, 0.26 [95% confidence interval, .22-.32]).

Keywords: COVID-19; Omicron variant; SARS-CoV-2.

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Figures

Figure 1.
Figure 1.
Hospitalization trends among patients with coronavirus disease 2019 (COVID-19) through different waves of severe acute respiratory syndrome coronavirus 2 variants. Trends in number of patients diagnosed with COVID-19 and percentage of patients with COVID-19 requiring hospitalization over time (14-day rolling average), stratified by vaccination status and location of COVID-19 diagnosis. Abbreviation: ED, emergency department.
See this image and copyright information in PMC

References

    1. Maslo C, Friedland R, Toubkin M, et al. Characteristics and outcomes of hospitalized patients in South Africa during the COVID-19 Omicron wave compared with previous waves. JAMA 2021; 327:583–4. - PMC - PubMed
    1. Christie B. Covid-19: early studies give hope Omicron is milder than other variants. BMJ 2021; 375:n3144. - PubMed
    1. Ferguson N, Ghani A, Hinsley W, Volz E. Hospitalisation risk for Omicron cases in England. Imperial College London. 2021. https://www.imperial.ac.uk/media/imperial-college/medicine/mrc-gida/2021.... Accessed 15 February 2022.
    1. Bhattacharyya RP, Hanage WP. Challenges in inferring intrinsic severity of the SARS-CoV-2 Omicron variant. N Engl J Med 2022; 386:e14. - PubMed
    1. Centers for Disease Control and Prevention . Variant proportions: COVID data tracker. https://covid.cdc.gov/covid-data-tracker/#variant-proportions. Accessed 14 January 2022.