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Observational Study
. 2022 Sep;21(9):3667-3672.
doi: 10.1111/jocd.15258. Epub 2022 Aug 9.

Cutaneous manifestations of Coronavirus Disease 2019

Rabia Ghafoor  1 , Syeda Mahanum Ali  1 , Mohamad Goldust  2
Affiliations
Observational Study

Cutaneous manifestations of Coronavirus Disease 2019

Rabia Ghafoor et al. J Cosmet Dermatol. 2022 Sep.

Erratum in

Abstract

Background: COVID-19 has been linked to a variety of dermatological conditions.

Objective: To determine the presence of various cutaneous manifestations in patients with COVID-19, also to define their features in relation to the systemic symptoms.

Methods: This research enrolled a total of 1206 lab-confirmed COVID-19 individuals at a tertiary-care hospital in Karachi, Pakistan. Expert dermatologists assessed patients for COVID-related skin conditions. COVID-19 severity was categorized as asymptomatic/mild, moderate, or severe.

Results: Of the 102 (85.7%) patients with only one cutaneous sign, 26.5% developed maculopapular/morbiliform/erythematous rash; 14.7% urticaria; 9.85% vesicular/pustular exanthem; 14.7% vascular pattern; 12.7% infections, 7.8% miscellaneous and 9.8% late cutaneous findings A longer-lasting vascular pattern was related with an older age and a fatal COVID-19 outcomes (P: 0.000) compared with mild/moderate disease. Most of the retiform purpura presented exclusively with thromboembolic episodes. The moderate severity was correlated with maculopapular/morbiliform/exanthematous phenotype (P: 0.009), whereas urticaria was attributed to asymptomatic/mild disease (0.001) compared with moderate/severe infection.

Limitations: Single-Center and observational study.

Conclusion: Vascular lesions were correlated with disastrous COVID-19 outcomes, whereas retiform purpura was linked to adverse outcomes. The maculopapular/morbiliform/erythematous rash was associated with moderate severity, while the urticarial rash was linked to milder course compared with moderate/severe severity infection.

Keywords: COVID-2019; corona virus; dermatology; global; pandemic.

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References

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