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Review
. 2022 Aug;38(3):483-500.
doi: 10.1016/j.cger.2022.03.001. Epub 2022 Mar 21.

Clinical Features of SARS-CoV-2 Infection in Older Adults

Francesca Remelli  1 , Stefano Volpato  2 , Caterina Trevisan  3
Affiliations
Review

Clinical Features of SARS-CoV-2 Infection in Older Adults

Francesca Remelli et al. Clin Geriatr Med. 2022 Aug.

Abstract

Covid-19 clinical presentation is extremely heterogenous, especially in older patients due to the possible presence of atypical symptoms, such as delirium, hyporexia and falls. The clinical characteristics at onset are influenced by the presence of common health-related conditions in older people, such as comorbidity, disability and frailty, and not simply by chronological age. Few studies investigated the tendency of Covid-19 symptoms to aggregate in cluster and the use of cluster approach might better describe the clinical complexity of the acute disease. Concerning the prognostic significance of Covid-19 clinical presentation in older people, the available literature still provides discordant results.

Keywords: Aged; Comorbidity; Frailty; Mortality; SARS-CoV-2; Symptom clusters; Symptoms.

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Conflict of interest statement

Disclosure The authors have nothing to disclose.

Figures

Fig. 1
Fig. 1
Symptoms and signs of SARS-CoV-2 infection.
Fig. 2
Fig. 2
Influencing factors of COVID-19 clinical presentation.
See this image and copyright information in PMC

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