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Review
. 2022 Aug;38(3):565-591.
doi: 10.1016/j.cger.2022.04.004. Epub 2022 Jun 20.

Nutraceuticals and Dietary Supplements for Older Adults with Long COVID-19

Matteo Tosato  1 , Francesca Ciciarello  1 , Maria Beatrice Zazzara  1 , Cristina Pais  1 , Giulia Savera  1 , Anna Picca  1 , Vincenzo Galluzzo  1 , Hélio José Coelho-Júnior  2 , Riccardo Calvani  3 , Emanuele Marzetti  4 , Francesco Landi  4 ; Gemelli Against COVID-19 Post-Acute Care Team
Affiliations
Review

Nutraceuticals and Dietary Supplements for Older Adults with Long COVID-19

Matteo Tosato et al. Clin Geriatr Med. 2022 Aug.

Abstract

The persistence of COVID-19 symptoms weeks or months after an initial SARS-CoV-2 infection has become one of the most burdensome legacies of the pandemic. This condition, known as long COVID syndrome, affects many persons of all age groups and is associated with substantial reductions of quality of life. Several mechanisms may be involved in long COVID syndrome, including chronic inflammation, metabolic perturbations, endothelial dysfunction, and gut dysbiosis. These pathogenic mechanisms overlap with those of the aging process and may aggravate pre-existing degenerative conditions. This review discusses bioactive foods, supplements, and nutraceuticals as possible interventions against long COVID syndrome.

Keywords: Bioactive foods; Fatigue; Frailty; Geriatrics; Gerontology; Nutrition; Sarcopenia; Therapy.

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Figures

Fig. 1
Fig. 1
Long COVID pathophysiological processes potentially targeted by the nutraceuticals and dietary supplements described in the study.
See this image and copyright information in PMC

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Further Reading

    1. Hashimoto Shoji, Yoshizaki Kazuyuki, Uno Kazuko, et al. Prompt Reduction in CRP, IL-6, IFN-γ, IP-10, and MCP-1 and a Relatively Low Basal Ratio of Ferritin/CRP Is Possibly Associated With the Efficacy of Tocilizumab Monotherapy in Severely to Critically Ill Patients With COVID-19. Frontiers in medicine. 2021;8 doi: 10.3389/fmed.2021.734838. - DOI - PMC - PubMed