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Case Reports
. 2022 Jul 22;15(7):e251138.
doi: 10.1136/bcr-2022-251138.

Marine-Lenhart syndrome with a cold nodule: an uncommon entity

Bharath Bopanna Kotramada  1 , Ami Mehul Mehta  1 , Sumeet Suresh Malapure  2 , Sharath P Madhyastha  3 , Kanthilatha Pai  4
Affiliations
Case Reports

Marine-Lenhart syndrome with a cold nodule: an uncommon entity

Bharath Bopanna Kotramada et al. BMJ Case Rep. .
No abstract available

Keywords: hyperthyroidism; pathology; thyroid disease.

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Conflict of interest statement

Competing interests: None declared.

Figures

Figure 1
Figure 1
Technetium 99 thyroid scan showing diffuse enlargement of both lobes of the thyroid gland along with focal increase in radiotracer uptake in the mid zone of right lobe. Focal photopenic area also noted in the mid zone of left lobe. Rest of the thyroid gland shows diffusely increased radiotracer uptake. (A): Anterior, (B: Right anterior oblique, C: Left anterior oblique.
Figure 2
Figure 2
Fine Needle Aspiration Cytology (FNAC) thyroid shows monolayered clusters of follicular cells against a background of colloid and macrophages, suggestive of Colloid goitre, 100×, Papanicolou stain.
Figure 3
Figure 3
Smear shows clusters of follicular cells with abundant pale cytoplasm, enlarged nuclei and infiltrated by lymphocytes, suggesting possibility of Graves’s disease. 200×, Papanicolou stain.
See this image and copyright information in PMC

References

    1. Builes Barrera CA, Castaño PA, Herrera Revollo P, et al. . Type 2 Marine-Lenhart syndrome: an uncommon cause of thyrotoxicosis. Cureus 2021;13:e20558. 10.7759/cureus.20558 - DOI - PMC - PubMed
    1. Neuman D, Kuker R, Vendrame F. Marine-Lenhart syndrome: case report, diagnosis, and management. Case Rep Endocrinol 2018;2018:1–4. 10.1155/2018/3268010 - DOI - PMC - PubMed
    1. Oka K, Yasuda M, Shien T, et al. . A marked goiter involved in Marine-Lenhart syndrome. J Gen Fam Med 2019;20:37–8. 10.1002/jgf2.220 - DOI - PMC - PubMed
    1. Agrawal K, Patro PSS, Meher BR, et al. . Prevalence of Marine-Lenhart syndrome on 99mTc-thyroid scintigraphy and response to radioiodine: A single institutional retrospective study. World J Nucl Med 2021;20:369–73. 10.4103/wjnm.wjnm_130_20 - DOI - PMC - PubMed

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