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Comment
. 2022 Sep;18(9):497-498.
doi: 10.1038/s41584-022-00817-0.

Discontinuing methotrexate to enhance vaccine response

Ana C Medeiros-Ribeiro  1 , Nadia E Aikawa  2   3
Affiliations
Comment

Discontinuing methotrexate to enhance vaccine response

Ana C Medeiros-Ribeiro et al. Nat Rev Rheumatol. 2022 Sep.

Abstract

In patients with autoimmune rheumatic disease, methotrexate therapy has been associated with poor immune response to vaccines, including those intended to provide protection against COVID-19. Emerging evidence supports the practice of temporarily discontinuing this treatment in order to improve immunogenicity.

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Conflict of interest statement

The authors declare no competing interests.

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Comment on

References

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