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. 2022 Oct;26(10):6061-6078.
doi: 10.1007/s00784-022-04639-y. Epub 2022 Jul 25.

Occlusion effects of bioactive glass and hydroxyapatite on dentinal tubules: a systematic review

S Behzadi  1 , Y Mohammadi  2 , L Rezaei-Soufi  3 , A Farmany  4   5
Affiliations

Occlusion effects of bioactive glass and hydroxyapatite on dentinal tubules: a systematic review

S Behzadi et al. Clin Oral Investig. 2022 Oct.

Abstract

Objective: Bioactive glass and hydroxyapatite are biocompatible materials used as an adjunct to various dental materials. The present study aimed to evaluate the occlusion effects of bioactive glasses and hydroxyapatite on dental tubules.

Materials and methods: We searched the PubMed/Medline, Embase, and Web of Science databases for the relevant records. The methodological quality of the studies was assessed by an accepted quality assessment tool.

Results: From the electronic databases, 372 articles were retrieved. After evaluating the records, 35 in vitro studies were included. The studies revealed a low risk of bias. The primary outcomes from bioactive glass studies demonstrated the potential efficacy of both bioactive glass and hydroxyapatite in dentin tubule occlusion compared to the control.

Conclusion: The current systematic review showed that bioactive glass and hydroxyapatite could effectively occlude the dentinal tubules. Thus, desensitizing agents containing bioactive glass and hydroxyapatite can be used to manage dentin hypersensitivity (DH). However, long-term follow-up clinical trials are required in the future before definitive recommendations can be made.

Clinical relevance: This work achieved a satisfactorily systematic review for assessing desensitizing agents containing bioactive glass and hydroxyapatite in dentine hypersensitivity treatments recommended for clinical practice and research.

Keywords: Bioactive glass; Dentin hypersensitivity; Dentin tubule occlusion; Hydroxyapatites.

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References

    1. Holland G, Narhi M, Addy M, Gangarosa L, Orchardson R (1997) Guidelines for the design and conduct of clinical trials on dentine hypersensitivity. J Clin Periodontol 24(11):808–813 - PubMed - DOI
    1. Addy M (2002) Dentine hypersensitivity: new perspectives on an old problem. Int Dent J 52(S2P2):367–75 - DOI
    1. Zeola LF, Soares PV, Cunha-Cruz J (2019) Prevalence of dentin hypersensitivity: Systematic review and meta-analysis. J Dent 81:1–6 - DOI
    1. Olley R, Sehmi H (2017) The rise of dentine hypersensitivity and tooth wear in an ageing population. Br Dent J 223(4):293 - PubMed - DOI
    1. Silva MS, ANdAN L, Pereira MMA, Ferraz Mendes R, Prado Júnior RR (2019) Prevalence and predictive factors of dentin hypersensitivity in Brazilian adolescents. J Clin Periodontology 46(4):448–56 - DOI

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