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. 2022 Jul 6:13:943993.
doi: 10.3389/fendo.2022.943993. eCollection 2022.

Cushing's Disease Management: Glimpse Into 2051

Rinkoo Dalan  1   2 , Stefan R Bornstein  2   3   4   5 , Bernhard O Boehm  2
Affiliations

Cushing's Disease Management: Glimpse Into 2051

Rinkoo Dalan et al. Front Endocrinol (Lausanne). .

Abstract

Major advancements are expected in medicine and healthcare in the 21st century- "Digital Age", mainly due to the application of data technologies and artificial intelligence into healthcare. In this perspective article we share a short story depicting the future Cushings' Disease patient and the postulated diagnostic and management approaches. In the discussion, we explain the advances in recent times which makes this future state plausible. We postulate that endocrinology care will be completely reinvented in the Digital Age.

Keywords: Cushings disease; circadian rhythms; digital; future; technology development.

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Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Figures

Figure 1
Figure 1
Deep Analytics interface showing the difference in daily patterns. Blood Pressure: Systolic and Diastolic blood pressure has a diurnal circadian rhythm with a nocturnal dip in the month of May; this dip is decreased in the month of June with an overall increase. Heart Rate is trending overall higher in June when compared to May. Heart Rate Variability assumed to be time interval (RR interval) is normally highest at night and lower in the early morning with subsequent increase as seen in May. This pattern is attenuated with an overall decrease in June. Glucose monitoring shows an overall baseline increase in glucose and the nocturnal dips are attenuated with post-prandial surge. Cortisol day curve shows attenuation of the circadian rhythm and overall very high levels.
See this image and copyright information in PMC

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