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Case Reports
. 2022 Jun 20;14(6):e26138.
doi: 10.7759/cureus.26138. eCollection 2022 Jun.

Neuromyelitis Optica Spectrum Disorder and Autoimmune Rheumatological Diseases: A Report of Two Cases and Literature Review

Mohannad Faisal  1 , Ahmad Matarneh  1 , Israa Alshahwani  2 , Omar Al-Allaf  3 , Abdul-Wahab Al-Allaf  4
Affiliations
Case Reports

Neuromyelitis Optica Spectrum Disorder and Autoimmune Rheumatological Diseases: A Report of Two Cases and Literature Review

Mohannad Faisal et al. Cureus. .

Abstract

Neuromyelitis optica spectrum disorder (NMOSD) is a rare autoimmune disorder, and its association with other autoinflammatory diseases has been reported in this study. In this article, we are discussing two patients with neuromyelitis optica who show evidence of autoimmune rheumatic diseases. The first case presented with acute myelitis and was diagnosed with NMOSD; she developed clinical features of Behçet's disease during follow-up, making it the second reported case worldwide. The second case presented with neuromyelitis optica and was found to have strongly positive Sjogren's serology.

Keywords: behcet’s syndrome; devic's disease; neuromyelitis optica spectrum disorder; nmosd; rheumatology & autoimmune diseases; sjogren’s syndrome.

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Conflict of interest statement

The authors have declared that no competing interests exist.

Figures

Figure 1
Figure 1. MRI of the cervical spine
A long segment of heterogeneously bright T2 signal intensity in the cervical spinal cord extending from C2 down to C7 vertebral level with mild cord expansion. MRI: Magnetic resonance imaging.
Figure 2
Figure 2. MRI of the cervical spine showing the reduction in T2 hyperintensity of intramedullary abnormal signal intensity extending from C2 to C7 level
MRI: Magnetic resonance imaging.
See this image and copyright information in PMC

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