Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2022 Jul 18;12(7):240.
doi: 10.3390/bs12070240.

Domains of Vulnerability, Resilience, Health Habits, and Mental and Physical Health for Health Disparities Research

Affiliations

Domains of Vulnerability, Resilience, Health Habits, and Mental and Physical Health for Health Disparities Research

Rebecca M Wolfe et al. Behav Sci (Basel). .

Abstract

Health disparities associated with severe mental illness (SMI) have become a major public health concern. The disparities are not directly due to the SMI. They involve the same leading causes of premature death as in the general population. The causes of the disparities are therefore suspected to reflect differences in health-related behavior and resilience. As with other problems associated with SMI, studying non-clinical populations at risk for future onset provides important clues about pathways, from vulnerability to unhealthy behavior and compromised resilience, to poor health and reduced quality of life. The purpose of this study was to identify possible pathways in a sample of public university students. Four domains of biosystemic functioning with a priori relevance to SMI-related vulnerability and health disparities were identified. Measures reflecting various well-studied constructs within each domain were factor-analyzed to identify common sources of variance within the domains. Relationships between factors in adjacent domains were identified with linear multiple regression. The results reveal strong relationships between common factors across domains that are consistent with pathways from vulnerability to health disparities, to reduced quality of life. Although the results do not provide dispositive evidence of causal pathways, they serve as a guide for further, larger-scale, longitudinal studies to identify causal processes and the pathways they follow to health consequences.

Keywords: health behaviors; health disparities; quality of life; schizotypy; vulnerability models.

PubMed Disclaimer

Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Pathways across domains identified by multiple regressions; percent figures indicate variance accounted for (R2 of the multiple regression solution) by factors in the previous domain.

Similar articles

Cited by

References

    1. Brown S., Inskip H., Barraclough B. Causes of the Excess Mortality of Schizophrenia. Br. J. Psychiatry. 2000;177:212–217. doi: 10.1192/bjp.177.3.212. - DOI - PubMed
    1. Colton C.W., Manderscheid R.W. Congruencies in Increased Mortality Rates, Years of Potential Life Lost, and Causes of Death Among Public Mental Health Clients in Eight States. Prev. Chronic Dis. 2006;3:14. - PMC - PubMed
    1. Crump C., Winkleby M.A., Sundquist K., Sundquist J. Comorbidities and Mortality in Persons with Schizophrenia: A Swedish National Cohort Study. AJP. 2013;170:324–333. doi: 10.1176/appi.ajp.2012.12050599. - DOI - PubMed
    1. Druss B.G., Zhao L., Von Esenwein S., Morrato E.H., Marcus S.C. Understanding Excess Mortality in Persons with Mental Illness: 17-Year Follow Up of a Nationally Representative US Survey. Med. Care. 2011;49:599–604. doi: 10.1097/MLR.0b013e31820bf86e. - DOI - PubMed
    1. Goff D.C., Sullivan L.M., McEvoy J.P., Meyer J.M., Nasrallah H.A., Daumit G.L., Lamberti S., D’Agostino R.B., Stroup T.S., Davis S., et al. A Comparison of Ten-Year Cardiac Risk Estimates in Schizophrenia Patients from the CATIE Study and Matched Controls. Schizophr. Res. 2005;80:45–53. doi: 10.1016/j.schres.2005.08.010. - DOI - PubMed