SGLT2 Inhibitors: From Antihyperglycemic Agents to All-Around Heart Failure Therapy

Stefan D Anker^{1

2}, Muhammad Shariq Usman³, Javed Butler^{3

4}

Affiliations

¹ Department of Cardiology and Berlin Institute of Health Center for Regenerative Therapies (BCRT), German Centre for Cardiovascular Research (DZHK) partner site Berlin, Charité Universitätsmedizin Berlin, Germany (S.D.A.).
² Institute of Heart Diseases, Wrocław Medical University, Poland (S.D.A.).
³ Department of Medicine, University of Mississippi, Jackson (M.S.U., J.B.).
⁴ Baylor Scott and White Research Institute, Dallas, TX (J.B.).

Editorial

Stefan D Anker et al. Circulation. 2022.

. 2022 Jul 26;146(4):299-302.

doi: 10.1161/CIRCULATIONAHA.122.060348. Epub 2022 Jul 25.

Stefan D Anker^{1

2}, Muhammad Shariq Usman³, Javed Butler^{3

4}

¹ Department of Cardiology and Berlin Institute of Health Center for Regenerative Therapies (BCRT), German Centre for Cardiovascular Research (DZHK) partner site Berlin, Charité Universitätsmedizin Berlin, Germany (S.D.A.).
² Institute of Heart Diseases, Wrocław Medical University, Poland (S.D.A.).
³ Department of Medicine, University of Mississippi, Jackson (M.S.U., J.B.).
⁴ Baylor Scott and White Research Institute, Dallas, TX (J.B.).

No abstract available

Keywords: Editorials; clinical trials; diabetes; heart failure; mortality; sodium glucose co-transporter 2 inhibitors.

Comment on

Effects of Empagliflozin on Symptoms, Physical Limitations, and Quality of Life in Patients Hospitalized for Acute Heart Failure: Results From the EMPULSE Trial.
Kosiborod MN, Angermann CE, Collins SP, Teerlink JR, Ponikowski P, Biegus J, Comin-Colet J, Ferreira JP, Mentz RJ, Nassif ME, Psotka MA, Tromp J, Brueckmann M, Blatchford JP, Salsali A, Voors AA. Kosiborod MN, et al. Circulation. 2022 Jul 26;146(4):279-288. doi: 10.1161/CIRCULATIONAHA.122.059725. Epub 2022 Apr 4. Circulation. 2022. PMID: 35377706 Free PMC article. Clinical Trial.
Effects of Early Empagliflozin Initiation on Diuresis and Kidney Function in Patients With Acute Decompensated Heart Failure (EMPAG-HF).
Schulze PC, Bogoviku J, Westphal J, Aftanski P, Haertel F, Grund S, von Haehling S, Schumacher U, Möbius-Winkler S, Busch M. Schulze PC, et al. Circulation. 2022 Jul 26;146(4):289-298. doi: 10.1161/CIRCULATIONAHA.122.059038. Epub 2022 Jun 29. Circulation. 2022. PMID: 35766022 Clinical Trial.