An Immune Checkpoint Inhibitor Heart: How CD45RA⁺ Effector Memory CD8⁺ T Cells (Temra) Are Implicated in Immune Checkpoint Inhibitor Myocarditis

Marinos Kallikourdis^{1

2}, Gianluigi Condorelli^{1

3}

Affiliations

¹ Humanitas University, Pieve Emanuele, Italy (M.K., G.C.).
² Adaptive Immunity Laboratory (M.K.), Humanitas Research Hospital IRCCS, Rozzano, Italy.
³ Cardio Center (G.C.), Humanitas Research Hospital IRCCS, Rozzano, Italy.

Editorial

Marinos Kallikourdis et al. Circulation. 2022.

. 2022 Jul 26;146(4):336-338.

doi: 10.1161/CIRCULATIONAHA.122.060788. Epub 2022 Jul 25.

Marinos Kallikourdis^{1

2}, Gianluigi Condorelli^{1

3}

¹ Humanitas University, Pieve Emanuele, Italy (M.K., G.C.).
² Adaptive Immunity Laboratory (M.K.), Humanitas Research Hospital IRCCS, Rozzano, Italy.
³ Cardio Center (G.C.), Humanitas Research Hospital IRCCS, Rozzano, Italy.

No abstract available

Keywords: CD8-positive T-lymphocytes; Editorials; chemokines; immune checkpoint inhibitors; immunotherapy; myocarditis.

Comment on

Identification of Pathogenic Immune Cell Subsets Associated With Checkpoint Inhibitor-Induced Myocarditis.
Zhu H, Galdos FX, Lee D, Waliany S, Huang YV, Ryan J, Dang K, Neal JW, Wakelee HA, Reddy SA, Srinivas S, Lin LL, Witteles RM, Maecker HT, Davis MM, Nguyen PK, Wu SM. Zhu H, et al. Circulation. 2022 Jul 26;146(4):316-335. doi: 10.1161/CIRCULATIONAHA.121.056730. Epub 2022 Jun 28. Circulation. 2022. PMID: 35762356 Free PMC article.