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Case Reports
. 2022 Jul 25;15(7):e250370.
doi: 10.1136/bcr-2022-250370.

Precalcific phase of pulmonary alveolar microlithiasis

Ahmed Aljishi  1 , Suha H Al-Badr  2 , Najla Aldaoud  3   4 , Rayid Abdulqawi  5   6
Affiliations
Case Reports

Precalcific phase of pulmonary alveolar microlithiasis

Ahmed Aljishi et al. BMJ Case Rep. .
No abstract available

Keywords: interstitial lung disease; pathology; radiology.

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Conflict of interest statement

Competing interests: None declared.

Figures

Figure 1
Figure 1
(A and C) High-resolution CT shows extensive bilateral poorly defined centrilobular ground-glass nodules. (B) No calcification is evident on the soft tissue window. (D) Chest X-Ray showing diffuse bilateral pulmonary nodules. (E) An old chest X-ray taken 9 years prior to presentation does not demonstrate appreciable changes over the years.
Figure 2
Figure 2
(A) Low-power magnification of alveolar spaces with calcification inside some of them (arrows). (B) Medium-power magnification of the lung parenchyma showing intra-alveolar concentric calcification (arrows) in contrast to the empty alveolar space (asterisk). (C) High-power magnification showing centrally lamellated calcified bodies (arrows). (D) Bronchoalveolar lavage showing numerous macrophages and lymphocytes with a calcific body (arrow) (Giemsa stain 200× magnification).
See this image and copyright information in PMC

References

    1. Huqun IS, Izumi S, Miyazawa H, Ishii K, et al. . Mutations in the SLC34A2 gene are associated with pulmonary alveolar microlithiasis. Am J Respir Crit Care Med 2007;175:263–8. 10.1164/rccm.200609-1274OC - DOI - PubMed
    1. Castellana G, Castellana G, Gentile M, et al. . Pulmonary alveolar microlithiasis: review of the 1022 cases reported worldwide. Eur Respir Rev 2015;24:607–20. 10.1183/16000617.0036-2015 - DOI - PMC - PubMed
    1. Bendstrup E, Jönsson Åsa Lina M,. Pulmonary alveolar microlithiasis: no longer in the stone age. ERJ Open Res 2020;6:00289-2020–20. 10.1183/23120541.00289-2020 - DOI - PMC - PubMed

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