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Book

Tarlov Cyst

In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan.
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Affiliations
Book

Tarlov Cyst

Yizhe Lim et al.

Excerpt

Tarlov cysts are perineural cysts between the perineurium and endoneurium, arising near the dorsal root ganglion. They can occur anywhere in the spine but most frequently around the sacral nerve roots, with S2 being the most common level. The cysts are usually filled with cerebrospinal fluid but may contain blood if there is a hemorrhagic complication. They are mostly asymptomatic but can present as chronic back pain in the sacral or coccyx area and may have radiculopathy or red flag features such as leg weakness, bowel and bladder dysfunction, and sexual dysfunction. The features may also be acute, especially if cyst complications like rupture or hemorrhage occur.

It was originally described on autopsy findings in 1938 by American neurosurgeon Dr. Isadore Tarlov.

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Conflict of interest statement

Disclosure: Yizhe Lim declares no relevant financial relationships with ineligible companies.

Disclosure: Wisam Selbi declares no relevant financial relationships with ineligible companies.

References

    1. Chaiyabud P, Suwanpratheep K. Symptomatic Tarlov cyst: report and review. J Med Assoc Thai. 2006 Jul;89(7):1047-50. - PubMed
    1. Klepinowski T, Orbik W, Sagan L. Global incidence of spinal perineural Tarlov's cysts and their morphological characteristics: a meta-analysis of 13,266 subjects. Surg Radiol Anat. 2021 Jun;43(6):855-863. - PMC - PubMed
    1. Fletcher-Sandersjöö A, Mirza S, Burström G, Pedersen K, Kuntze Söderqvist Å, Grane P, Fagerlund M, Edström E, Elmi-Terander A. Management of perineural (Tarlov) cysts: a population-based cohort study and algorithm for the selection of surgical candidates. Acta Neurochir (Wien) 2019 Sep;161(9):1909-1915. - PMC - PubMed
    1. Soon WC, Sun R, Czyz M. Haemorrhagic Tarlov cyst: A rare complication of anticoagulation therapy. Oxf Med Case Reports. 2021 Aug;2021(8):omab063. - PMC - PubMed
    1. Lucantoni C, Than KD, Wang AC, Valdivia-Valdivia JM, Maher CO, La Marca F, Park P. Tarlov cysts: a controversial lesion of the sacral spine. Neurosurg Focus. 2011 Dec;31(6):E14. - PubMed

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