Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2022 Nov 30;18(6):2104571.
doi: 10.1080/21645515.2022.2104571. Epub 2022 Jul 26.

Evaluating the quality of HPV vaccine-related information on the Portuguese Internet

Affiliations

Evaluating the quality of HPV vaccine-related information on the Portuguese Internet

Michael Zarnowski Passos et al. Hum Vaccin Immunother. .

Abstract

Human papillomavirus (HPV) is considered the second largest human carcinogen after tobacco and is responsible for 5% of all cancers, 10% of cancers in women, and 15% of all cancers in developing countries. Among these, cervical cancer is the most prevalent. An HPV vaccine has recently been developed to provide primary protection against the viral infection. In 2014, Brazil's National Immunization Program (Programa Nacional de Imunizações, PNI) started making a quadrivalent vaccine available to the public. However, after 2014, the vaccine coverage dropped and did not reach the PNI's targets. Among other factors, this low uptake was due to the quality of information on the Internet. Using Google Trends, the main search terms used to search for vaccine-related information on the Internet were identified. The content of the identified websites was analyzed using the DISCERN instrument and their reach was determined using their page authority score. Most of the texts analyzed were not of high quality. The data that most commonly reach the lay public are from sites that lack scientific rigor. We found a weak correlation between the DISCERN and page authority scores. Based on our analysis, we inferred that the information that reaches the user is not always the most accurate and can lead to harmful decisions on vaccination. The content that reaches the user most easily is not always of sound quality. New analyses are important, especially on the impact of social networks that present even fewer criteria in publications and are more easily accessible.

Keywords: HPV; Internet; Vaccine; online; quality of information.

PubMed Disclaimer

Conflict of interest statement

No potential conflict of interest was reported by the author(s).

Figures

Figure 1.
Figure 1.
Flowchart showing division of sites according to inclusion and exclusion criteria.
Figure 2.
Figure 2.
Distribution by group of sites surveyed.
Figure 3.
Figure 3.
Average grades assigned to the reliability, quality, and total score dimensions.
Figure 4.
Figure 4.
Correlation analysis between sum of total DISCERN and PA scores.

References

    1. Sasagawa T, Takagi H, Makinoda S.. Immune responses against human papillomavirus (HPV) infection and evasion of host defense in cervical cancer. J Infect Chemother. 2012;18(6):1–6. doi:10.1007/s10156-012-0485-5. - DOI - PubMed
    1. Winer RL, Lee S-K, Hughes JP, Adam DE, Kiviat NB, Koutsky LA. Genital human papillomavirus infection: Incidence and risk factors in a cohort of female university students. Am J Epidemiol. 2003;157(3):218–226. doi:10.1093/aje/kwf180. - DOI - PubMed
    1. WHO/ICO Information Centre on HPV and Cervical Cancer (HPV Information Centre) . Human papillomavirus and related cancers in world. Summary report 2018; [accessed 2021 Aug 20]. https://www.who.int/health-topics/cervical-cancer#tab=tab_1.
    1. Instituto Nacional de Câncer . Estimate 2020: incidence of cancer in Brazil/Instituto Nacional de Câncer José Alencar Gomes da Silva. Coordenação de Prevenção e Vigilância. Rio de Janeiro: INCA; 2017. [accessed 2021 Jun 5]. http://www1.inca.gov.br/inca/Arquivos/estimativa-2020.pdf
    1. Stanley M, Gissmann L, Nardelli-Haefliger D. Immunobiology of human papillomavirus infection and vaccination: implications for second-generation vaccines. Vaccine. 2008;26(10):K62–67. doi:10.1016/j.vaccine.2008.05.066. - DOI - PubMed

Substances