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Review
. 2022:1370:3-21.
doi: 10.1007/978-3-030-93337-1_1.

The Disease-Modifying Role of Taurine and Its Therapeutic Potential in Coronavirus Disease 2019 (COVID-19)

Larissa E van Eijk  1 , Annette K Offringa  2 , Maria-Elena Bernal  3 , Arno R Bourgonje  4 , Harry van Goor  1 , Jan-Luuk Hillebrands  1
Affiliations
Review

The Disease-Modifying Role of Taurine and Its Therapeutic Potential in Coronavirus Disease 2019 (COVID-19)

Larissa E van Eijk et al. Adv Exp Med Biol. 2022.

Abstract

Taurine is an amino sulfonic acid that is implicated in numerous physiological functions, including the regulation of oxidative stress, which plays an important role in coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), together with other pathophysiological processes. The recent finding of decreased serum taurine levels in SARS-CoV-2-infected patients, in tandem with its potential modulatory role in COVID-19 due to its antiviral, antioxidant, anti-inflammatory, and vascular-related effects, provides a rationale for considering taurine as a beneficial supplement in patients suffering from COVID-19. Here, we reviewed the potential disease-modifying effects of taurine and combined these with the current knowledge on COVID-19 to clarify the potential role of taurine in this respiratory disease.

Keywords: Coronavirus disease 2019 (COVID-19); Inflammation; Oxidative stress; Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); Taurine; Treatment.

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