Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2022 Jul 26;12(1):298.
doi: 10.1038/s41398-022-02072-z.

n-3 PUFAs for depression: treatment effect or absence-of-placebo effect?

Arian Memarpouri  1   2 , Willem van der Does  1   3 , Marc L Molendijk  4   5
Affiliations
Comment

n-3 PUFAs for depression: treatment effect or absence-of-placebo effect?

Arian Memarpouri et al. Transl Psychiatry. .
No abstract available

PubMed Disclaimer

Conflict of interest statement

The authors declare no competing interests.

Comment on

  • Efficacy of omega-3 PUFAs in depression: A meta-analysis.
    Liao Y, Xie B, Zhang H, He Q, Guo L, Subramanieapillai M, Fan B, Lu C, McIntyre RS. Liao Y, et al. Transl Psychiatry. 2019 Aug 5;9(1):190. doi: 10.1038/s41398-019-0515-5. Transl Psychiatry. 2019. PMID: 31383846 Free PMC article. Review.

References

    1. Liao Y, Xie B, Zhang H, He Q, Guo L, Subramaniapillai M, et al. Efficacy of omega-3 PUFAs in depression: a meta-analysis. Trans Psychiatry. 2019;9:190. - PMC - PubMed
    1. Jazayeri S, Tehrani-Doost M, Keshavarz SA, Hosseini M, Djazayery A, Amini H, et al. Comparison of therapeutic effects of omega-3 fatty acid eicosapentaenoic acid and fluoxetine, separately and in combination, in major depressive disorder. Aus NZ J Psychiatry. 2008;42:192–8. doi: 10.1080/00048670701827275. - DOI - PubMed
    1. Gertsik L, Poland RE, Bresee C, Rapaport MH. Omega-3 fatty acid augmentation of citalopram treatment for patients with major depressive disorder. J Clin Psychopharmacol. 2012;32:61–4. doi: 10.1097/JCP.0b013e31823f3b5f. - DOI - PMC - PubMed
    1. Antypa N, Smelt AHM, Strengholt A, Van Der Does AJW. Effects of omega-3 fatty acid supplementation on mood and emotional information processing in recovered depressed individuals. J Psychopharmacol. 2012;26:738–43. doi: 10.1177/0269881111424928. - DOI - PubMed
    1. Mischoulon D, Nierenberg AA, Schettler PJ, Kinkead BL, Fehling K, Martinson MA, et al. A double-blind, randomized controlled clinical trial comparing eicosapentaenoic acid versus docosahexaenoic acid. J Clin Psychiatry. 2015;76:54–61. doi: 10.4088/JCP.14m08986. - DOI - PMC - PubMed

MeSH terms

Substances