PARP11 interfer(on)es with CAR T cell efficacy

Isabelle Munoz^{1

2}, Paul A Beavis^{3

4}

Affiliations

¹ Cancer Immunology Program, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.
² Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, University of Melbourne, Parkville, Victoria, Australia.
³ Cancer Immunology Program, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia. paul.beavis@petermac.org.
⁴ Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, University of Melbourne, Parkville, Victoria, Australia. paul.beavis@petermac.org.

Comment

Isabelle Munoz et al. Nat Cancer. 2022 Jul.

. 2022 Jul;3(7):790-792.

doi: 10.1038/s43018-022-00406-w.

Isabelle Munoz^{1

2}, Paul A Beavis^{3

4}

¹ Cancer Immunology Program, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.
² Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, University of Melbourne, Parkville, Victoria, Australia.
³ Cancer Immunology Program, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia. paul.beavis@petermac.org.
⁴ Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, University of Melbourne, Parkville, Victoria, Australia. paul.beavis@petermac.org.

No abstract available

Comment on

Targeting PARP11 to avert immunosuppression and improve CAR T therapy in solid tumors.
Zhang H, Yu P, Tomar VS, Chen X, Atherton MJ, Lu Z, Zhang HG, Li S, Ortiz A, Gui J, Leu NA, Yan F, Blanco A, Meyer-Ficca ML, Meyer RG, Beiting DP, Li J, Nunez-Cruz S, O'Connor RS, Johnson LR, Minn AJ, George SS, Koumenis C, Diehl JA, Milone MC, Zheng H, Fuchs SY. Zhang H, et al. Nat Cancer. 2022 Jul;3(7):808-820. doi: 10.1038/s43018-022-00383-0. Epub 2022 May 30. Nat Cancer. 2022. PMID: 35637402 Free PMC article.

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