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Review
. 2022 Jul 3;12(7):933.
doi: 10.3390/biom12070933.

Metal-Based Compounds in Antiviral Therapy

Chiara Abate  1 , Federica Carnamucio  1 , Ottavia Giuffrè  1 , Claudia Foti  1
Affiliations
Review

Metal-Based Compounds in Antiviral Therapy

Chiara Abate et al. Biomolecules. .

Abstract

In recent years, the study of metal complexes and metal-based nanomaterials has aroused particular interest, leading to the promotion of new effective systems for the abatement of various viral diseases. Starting from the analysis of chemical properties, this review focuses on the employment of metal-based nanoparticles as antiviral drugs and how this interaction leads to a substantial enhancement in antiviral activity. The use of metal-based antiviral drugs has also spread for the formulation of antiviral vaccines, thanks especially to the remarkable adjuvant activities of some of the metal complexes. In particular, the small size and inert nature of Au- and Ag-based nanoparticles have been exploited for the design of systems for antiviral drug delivery, leading to the development of specific and safe therapies that lead to a decrease in side effects.

Keywords: antiviral drugs; drug delivery; metal compounds; metal nanoparticles; vaccines.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Schematic representation of the main properties and applications of metal-based compounds.
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