Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2022 Jul 21;9(7):1098.
doi: 10.3390/children9071098.

Oral-Health-Related Quality of Life among Non-Syndromic School-Age Children with Orofacial Clefts: Results from a Cross-Sectional Study in Northern Italy

Affiliations

Oral-Health-Related Quality of Life among Non-Syndromic School-Age Children with Orofacial Clefts: Results from a Cross-Sectional Study in Northern Italy

Patrizia Defabianis et al. Children (Basel). .

Abstract

The aim of this cross-sectional study was to determine the influence of orofacial clefts on the oral-health-related quality of life (OHRQoL) in a group of Italian children and adolescents and to examine whether gender, age, cleft type, and surgical protocol were associated with patients' OHRQoL. A total of 71 patients with cleft lip and/or cleft palate (CLP) and 71 age- and gender-matched controls (aged 8 to 18 years) were asked to complete the Child Oral Health Impact Profile (COHIP), a validated and reliable questionnaire to assess self-reported OHRQoL in children and teenagers. Children with orofacial clefts showed statistically significant lower quality of life scores than controls for total OHRQoL and for each of the subscales. Gender, the type of cleft, and the type of surgical protocol had no significant influence on OHRQoL. The negative impact of CLP on the area of self-image was greater in 12-18-year-olds, indicating a higher need for psychosocial counselling. These findings suggest that Italian CLP children and adolescents experience a poorer OHRQoL in comparison to their non-cleft peers.

Keywords: COHIP; children; cleft; oral-health-related quality of life.

PubMed Disclaimer

Conflict of interest statement

The authors declare no conflict of interest.

Similar articles

Cited by

References

    1. Raut J., Simeone R.M., Tinker S.C., Canfiled M.A., Day R.S., Agopian A.J. Proportion of orofacial clefts attributable to recognized risk factors. Cleft Palate Craniofac. J. 2019;56:151–158. doi: 10.1177/1055665618774019. - DOI - PMC - PubMed
    1. Tolarova M.M., Cervenka J. Classification and birth prevalence of orofacial cleft. Am. J. Med. Genet. 1998;75:126–137. doi: 10.1002/(SICI)1096-8628(19980113)75:2<126::AID-AJMG2>3.0.CO;2-R. - DOI - PubMed
    1. Gundlach K.K., Maus C. Epidemiological studies on the frequency of clefts in Europe and worldwide. J. Cranio-Maxillofac. Surg. 2006;34((Suppl. 2)):1–2. doi: 10.1016/S1010-5182(06)60001-2. - DOI - PubMed
    1. James S.L., Abate K.H., Abate D., Abay S.M., Abbafati C., Abbasi N., Abbastabar H., Abd-Allah F., Abdela J., Abdelalim A., et al. Global, regional, and national incidence, prevalence, and years lived with disability for 354 diseases and injuries for 195 countries and territories, 1990–2017: A systematic analysis for the global burden of disease study 2017. Lancet. 2018;392:1789–1858. doi: 10.1016/S0140-6736(18)32279-7. - DOI - PMC - PubMed
    1. Worley M.L., Patel K.G., Kilpatrick L.A. Cleft Lip and Palate. Clin. Perinatol. 2018;45:661–678. doi: 10.1016/j.clp.2018.07.006. - DOI - PubMed

LinkOut - more resources