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. 2022 Jul 5;12(7):1641.
doi: 10.3390/diagnostics12071641.

Technical Performance, Overall Accuracy and Complications of EUS-Guided Interventional Procedures: A Dynamic Landscape

Irina Florina Cherciu Harbiyeli  1 , Alina Constantin  2 , Irina Mihaela Cazacu  1   3 , Daniela Elena Burtea  1 , Elena Codruța Gheorghe  1 , Carmen Florina Popescu  1 , Nona Bejinariu  4 , Claudia Valentina Georgescu  1 , Daniel Pirici  1 , Bogdan Silviu Ungureanu  1 , Cătălin Copăescu  2 , Adrian Săftoiu  1   2
Affiliations

Technical Performance, Overall Accuracy and Complications of EUS-Guided Interventional Procedures: A Dynamic Landscape

Irina Florina Cherciu Harbiyeli et al. Diagnostics (Basel). .

Abstract

Endoscopic ultrasound (EUS) gained wide acceptance as the diagnostic and minimally invasive therapeutic approach for intra-luminal and extraluminal gastrointestinal, as well as various non-gastrointestinal lesions. Since its introduction, EUS has undergone substantial technological advances. This multi-centric study is a retrospective analysis of a prospectively maintained database of patients who underwent EUS for the evaluation of lesions located within the gastrointestinal tract and the proximal organs. It aimed to extensively assess in dynamic the dual-center EUS experience over the course of the past 20 years. Hence, we performed a population study and an overall assessment of the EUS procedures. The performance of EUS-FNA/FNB in diagnosing pancreatic neoplasms was evaluated. We also investigated the contribution of associating contrast-enhanced ultrasound imaging (CE-EUS) with EUS-FNA/FNB for differentiating solid pancreatic lesions or cystic pancreatic lesions. A total of 2935 patients undergoing EUS between 2002-2021 were included, out of which 1880 were diagnostic EUS and 1052 EUS-FNA/FNB (80% FNA and 20% FNB). Therapeutic procedures performed included endoscopic transmural drainage of pancreatic fluid collections, celiac plexus block and neurolysis, while diagnostic EUS-like CE-EUS (20%) and real-time elastography (12%) were also conducted. Most complications occurred during the first 7 days after EUS-FNA/FNB or pseudocyst drainage. EUS and the additional tools have high technical success rates and low rates of complications. The EUS methods are safe, cost effective and indispensable for the diagnostic or therapeutic management in gastroenterological everyday practice.

Keywords: endoscopic ultrasound; endoscopic ultrasound-guided fine needle aspiration/biopsy.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Study design.
Figure 2
Figure 2
EUS assessment (%) with regard to lesion location.
Figure 3
Figure 3
CE-EUS image of a PDAC showing a hypoenhancing solid mass in both arterial and venous phase.
Figure 4
Figure 4
CE-EUS image of a MFP revealing a solid mass with hyperenhancement in the arterial phase and no wash-out in the venous phase.
Figure 5
Figure 5
CE-EUS image of a pNET revealing an isoenhancing solid mass in the arterial phase and a discrete wash-out in the venous phase.
Figure 6
Figure 6
CE-EUS image of a pNEC (pancreatic neuroendocrine carcinoma) with aspect in the arterial phase and wash-out in the venous phase.
Figure 7
Figure 7
Contrast enhancement of the cystic wall.
Figure 8
Figure 8
Contrast enhancement of a cystic septae.
Figure 9
Figure 9
Contrast enhancement of a cystic mural nodule.
See this image and copyright information in PMC

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