Correction: Yu et al. HPV16 and HPV18 Genome Structure, Expression, and Post-Transcriptional Regulation. Int. J. Mol. Sci. 2022, 23, 4943

Abstract

In the published review [...].

Figure 1

Papillomavirus genome structure, annotated ORFs, and conserved ACS in the origin of replication (Ori). (a) HPV16 genome and annotated ORFs. The non-structural proteins from the early region of the genome, including E1, E2, E1^E4, E5, E6, E7, and E8^E2, are shown in purple. The viral capsid proteins, L1 and L2, from the late region of the genome are shown in blue. URR (yellow), upstream regulatory region. P_E and P_L mark the early and late promoters, and pA_E and pA_L stand for the early and late polyadenylation sites. (b) Conservation of the mammalian ARS consensus sequence (ACS) [16] in the Ori of selected papillomavirus genomes. Shown in this panel are conserved bases with position weight matrix (sequence logo bits) of the 167 predicted ACS elements [16] in comparison with the viral Ori sequences from the selected viral URR tail (red)-head (black) regions. Adapted with permission from Ref. [16]. Copyright 2018 Springer Nature. ARS—autonomously replicating sequence.