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. 2022 Aug;57(4):575-587.
doi: 10.1177/00185787211066463. Epub 2022 Jan 19.

Narrative Review: Addressing Covid-19 Vaccine Concerns in Special and Vulnerable Populations

Kent A Owusu  1   2 , Muhammad K Effendi  3 , Melissa L Thompson Bastin  4 , Samad Tirmizi  2 , Ishaq Lat  5 , Mahmoud A Ammar  2
Affiliations

Narrative Review: Addressing Covid-19 Vaccine Concerns in Special and Vulnerable Populations

Kent A Owusu et al. Hosp Pharm. 2022 Aug.

Abstract

Public health advocates and healthcare professionals (HCPs) have been challenged with vaccine hesitancy and addressing misinformation. In order for HCPs and pharmacists, in particular, to serve as effective stewards of COVID-19 vaccine science in the interest of the public good, it is imperative for HCPs to appreciate the various factors contributing to vaccine hesitancy and vaccine distrust. A PubMed search was performed and relevant articles on COVID-19 vaccine in populations of interest were included. Information from health agencies, such as the Centers for Disease Control and Prevention (CDC) as well as established professional health societies was incorporated for guidance. This review focuses on COVID-19 vaccine concerns in the populations of children, pregnancy and lactation, immunocompromised, and religious and ethnic disparities. We also discuss post emergency use authorization experience with respect to vaccine safety including annotations on Guillain-Barré Syndrome, myocarditis and pericarditis, and thrombosis with thrombocytopenia syndrome.

Keywords: education; infectious diseases; pediatrics; pharmacists; pregnancy/lactation; vaccines.

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Conflict of interest statement

Declaration of Conflicting Interests: The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

References

    1. Wolfe RM, Sharp LK. Anti-vaccinationists past and present. BMJ. 2002;325(7361):430-432. - PMC - PubMed
    1. Albert MR, Ostheimer KG, Breman JG. The last smallpox epidemic in Boston and the vaccination controversy, 1901-1903. N Engl J Med. 2001;344(5):375-379. - PubMed
    1. Walter EB, Talaat KR, Sabharwal C, et al.; C4591007 Clinical Trial Group. Evaluation of the BNT162b2 covid-19 vaccine in children 5 to 11 years of age. N Engl J Med. Published online November 9, 2021. doi: 10.1056/NEJMoa2116298 - DOI
    1. Gray KJ, Bordt EA, Atyeo C, et al. Coronavirus disease 2019 vaccine response in pregnant and lactating women: a cohort study. Am J Obstet Gynecol. 2021;225(3):303.e1-303.e17. - PMC - PubMed
    1. Agha ME, Blake M, Chilleo C, Wells A, Haidar G. Suboptimal response to coronavirus disease 2019 messenger RNA vaccines in patients with hematologic malignancies: a need for vigilance in the postmasking era. Open Forum Infect Dis. 2021;8(7):ofab353. - PMC - PubMed

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