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. 2022 Jul 12:9:908040.
doi: 10.3389/fcvm.2022.908040. eCollection 2022.

A Bibliometric and Visualized Analysis of Uremic Cardiomyopathy From 1990 to 2021

Jing-Fu Bao  1   2 , Pan-Pan Hu  1   2 , Qin-Ying She  3 , Difei Zhang  4 , Jia-Ju Mo  1   2 , Aiqing Li  1   2
Affiliations

A Bibliometric and Visualized Analysis of Uremic Cardiomyopathy From 1990 to 2021

Jing-Fu Bao et al. Front Cardiovasc Med. .

Abstract

Background: Uremic cardiomyopathy is commonly presented in chronic kidney disease (CKD), and it severely affects the prognosis of patients with CKD. In the past few decades, the investigation of uremic cardiomyopathy has developed rapidly. However, no report has summarized the situation of uremic cardiomyopathy research to date. This study aimed to evaluate the state of uremic cardiomyopathy research in the last 30 years and identify important topics and achievements, as well as emerging trends through bibliometric analysis.

Materials and methods: Publications related to uremic cardiomyopathy were collected from Science Citation Index Expanded. HistCite, VOSviewer, CiteSpace, and the Bibliometrix Package were used for bibliometric analysis and visualization, including the analysis of the overall distribution of the annual publication, leading countries, and active institutions and authors, core journals, co-cited references, and keywords.

Results: A total of 2,403 studies related to uremic cardiomyopathy were obtained, and progress related to uremic cardiomyopathy was slower in past 3 years. A total of 10,077 authors from 2,697 institutions in 89 countries or regions reported investigations on uremic cardiomyopathy. The United States of America was the most productive and the most cited country. Myles Wolf, Joseph I Shapiro, and Carmine Zoccali published most articles in uremic cardiomyopathy, and journals in nephrology possessed core status in the field. Phosphate metabolism was the hotspot in uremic cardiomyopathy research in recent years, and future progress may concentrate on phosphate metabolism, endogenous natriuretic factors, and novel biomarkers.

Conclusion: The United States of America and European countries played central roles in uremic cardiomyopathy research, while Chinese scholars should be more involved in this field. Global publications on uremic cardiomyopathy have entered platform stage, and the fibroblast growth factor-23-klotho axis remained a hotspot in this field. Endogenous natriuretic factors and novel biomarkers may be potential directions in future investigations.

Keywords: CiteSpace; HistCite; VOSviewer; bibliometric analysis; bibliometrix; uremic cardiomyopathy.

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Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Figures

FIGURE 1
FIGURE 1
Publication outputs and citations on uremic cardiomyopathy. (A) Global annual production trends. (B) Annual total global citation score (TGCS) and total local citation score (TLCS) of publications on uremic cardiomyopathy.
FIGURE 2
FIGURE 2
Leading countries in the uremic cardiomyopathy field. (A) Worldwide distribution of the publication. (B,C) Total citations and average publication citations of the top 10 productive countries. (D) Clustering of collaboration among countries. (E) Timeline visualization of collaboration among countries.
FIGURE 3
FIGURE 3
Active institutes and authors analysis. (A) Clustering of collaboration among institutes. (B) Density visualization of institutes based on the mean frequency of appearance and two groups with higher collaboration can be observed. (C) Timeline distribution of publications from the top 10 active authors. (D) Clustering of collaboration among authors. (E) Density visualization of authors based on the mean frequency of appearance and three groups with higher collaboration can be observed.
FIGURE 4
FIGURE 4
Core journals in the uremic cardiomyopathy field. (A) Clustering of co-citation among journals. (B) Density visualization of journals based on the mean frequency of appearance, and journals in nephrology possessed a core position in clustering.
FIGURE 5
FIGURE 5
Co-cited reference analysis. (A) Timeline distribution of 13 clusters with the higher K values. (B) The top 20 references with the higher citation bursts, references with the red box is directly associated with FGF-23.
FIGURE 6
FIGURE 6
Analysis of keywords in publications and milestones of the uremic cardiomyopathy field. (A) Major keywords evolution of uremic cardiomyopathy research. (B) Clustering of co-occurrence among keywords. (C) Timeline visualization of co-occurrence among keywords.
FIGURE 7
FIGURE 7
Major achievements in the uremic cardiomyopathy field.
See this image and copyright information in PMC

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