Open innovation: the key to advancing brain health

Harris A Eyre^{1

2

3

4

5

6

7

8}, Jason Searfoss⁹, Malcolm Hopwood^{10

11}, Michael Berk^{3

10

11

12}, Shuo Chen¹, Jeffrey Cummings¹³, Francois Veron¹⁴, Vicki Zikopoulou¹⁵, Agustin Ibanez^{6

7

8

16

17}, Kacie Kelly^{1

2}, Jair C Soares⁵, Erin Smith^{1

6

7

18}, Barnabas J Gilbert¹⁹

Affiliations

¹ Neuroscience-Inspired Policy Initiative, Organisation for Economic Co-Operation and Development and the PRODEO Institute, Paris, France.
² Meadows Mental Health Policy Institute, Dallas, TX, USA.
³ Institute for Mental and Physical Health and Clinical Translation (IMPACT), Deakin University, Geelong, VIC, Australia.
⁴ Department of Psychiatry, Baylor College of Medicine, Houston, TX, USA.
⁵ Department of Psychiatry, University of Texas Health Sciences Center at Houston, Houston, TX, USA.
⁶ Global Brain Health Institute, University of California, San Francisco, San Francisco, CA, USA.
⁷ Trinity College Dublin, Dublin, Ireland.
⁸ Latin American Brain Health Institute, Universidad Adolfo Ibáñez, Santiago, Chile.
⁹ Boomtown Accelerators, Boulder, CO, USA.
¹⁰ Department of Psychiatry, The University of Melbourne, Parkville, VIC, Australia.
¹¹ The Florey Institute for Neuroscience and Mental Health, The University of Melbourne, Parkville, VIC, Australia.
¹² ORYGEN Youth Health, The University of Melbourne, Parkville, VIC, Australia.
¹³ Chambers-Grundy Center for Transformative Neuroscience, Department of Brain Health, School of Integrated Health Sciences, University of Nevada, Las Vegas (UNLV), Henderson, NV, USA.
¹⁴ Newfund Capital, Paris, France.
¹⁵ Likeminds, Boston, MA, USA.
¹⁶ National Scientific and Technical Research Council, Buenos Aires, Argentina.
¹⁷ Cognitive Neuroscience Center, Universidad de San Andrés, Buenos Aires, Argentina.
¹⁸ School of Medicine, Stanford University, Palo Alto, CA, USA.
¹⁹ School of Medicine, Imperial College London, London, UK.

PMID: 35904045
PMCID: PMC9906564
DOI: 10.1017/S109285292200092X

Editorial

Open innovation: the key to advancing brain health

Harris A Eyre et al. CNS Spectr. 2023 Aug.

. 2023 Aug;28(4):392-394.

doi: 10.1017/S109285292200092X. Epub 2022 Jul 29.

Authors

Affiliations

¹ Neuroscience-Inspired Policy Initiative, Organisation for Economic Co-Operation and Development and the PRODEO Institute, Paris, France.
² Meadows Mental Health Policy Institute, Dallas, TX, USA.
³ Institute for Mental and Physical Health and Clinical Translation (IMPACT), Deakin University, Geelong, VIC, Australia.
⁴ Department of Psychiatry, Baylor College of Medicine, Houston, TX, USA.
⁵ Department of Psychiatry, University of Texas Health Sciences Center at Houston, Houston, TX, USA.
⁶ Global Brain Health Institute, University of California, San Francisco, San Francisco, CA, USA.
⁷ Trinity College Dublin, Dublin, Ireland.
⁸ Latin American Brain Health Institute, Universidad Adolfo Ibáñez, Santiago, Chile.
⁹ Boomtown Accelerators, Boulder, CO, USA.
¹⁰ Department of Psychiatry, The University of Melbourne, Parkville, VIC, Australia.
¹¹ The Florey Institute for Neuroscience and Mental Health, The University of Melbourne, Parkville, VIC, Australia.
¹² ORYGEN Youth Health, The University of Melbourne, Parkville, VIC, Australia.
¹³ Chambers-Grundy Center for Transformative Neuroscience, Department of Brain Health, School of Integrated Health Sciences, University of Nevada, Las Vegas (UNLV), Henderson, NV, USA.
¹⁴ Newfund Capital, Paris, France.
¹⁵ Likeminds, Boston, MA, USA.
¹⁶ National Scientific and Technical Research Council, Buenos Aires, Argentina.
¹⁷ Cognitive Neuroscience Center, Universidad de San Andrés, Buenos Aires, Argentina.
¹⁸ School of Medicine, Stanford University, Palo Alto, CA, USA.
¹⁹ School of Medicine, Imperial College London, London, UK.

PMID: 35904045
PMCID: PMC9906564
DOI: 10.1017/S109285292200092X

Abstract

With the exponential growth in investment attention to brain health-solutions spanning brain wellness to mental health to neurological disorders-tech giants, payers, and biotechnology companies have been making forays into this field to identify technology solutions and pharmaceutical amplifiers. So far, their investments have had mixed results. The concept of open innovation (OI) was first coined by Henry Chesbrough to describe the paradigm by which enterprises allow free flow of ideas, products, and services from the outside to the inside and vice versa in order to remain competitive, particularly in rapidly evolving fields where there is abundant, relevant knowledge outside the traditional walls of the enterprise. In this article, we advocate for further exploration and advancement of OI in brain health.

Keywords: Open innovation; brain health; closed innovation; corporate innovation; entrepreneurship; equity; venture capital.

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Figures

**Figure 1.**
Open versus closed innovation.

See this image and copyright information in PMC

References

1. Eyre HA, Berk M, Smith E, et al. Brain health executives: a transdisciplinary workforce innovation—A commentary. Innov Clin Neurosci 2021;18(4–6): 24–27. - PMC - PubMed
1. Chesbrough HW. Open Innovation: The New Imperative for Creating and Profiting from Technology. Boston, MA: Harvard Business Press; 2006.
1. Centre for Aging + Brain Health Innovation; 2022. https://www.cabhi.com/. Accessed November 7, 2022.
1. British Patient Capital; 2022. https://www.britishpatientcapital.co.uk/. Accessed November 7, 2022.
1. Smith E, Ali D, Wilkerson B, et al. A brain capital grand strategy: toward economic reimagination. Mol Psychiatry. 2021;26(1):3–22. - PMC - PubMed

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Open innovation: the key to advancing brain health

Affiliations

Open innovation: the key to advancing brain health

Authors

Affiliations

Abstract

Figures

References

Publication types

MeSH terms

Grants and funding

LinkOut - more resources

Full Text Sources