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Observational Study
. 2022 Jul 29;101(30):e29596.
doi: 10.1097/MD.0000000000029596.

Decreased door-to-balloon time in patients with ST-segment elevation myocardial infarction during the early COVID-19 pandemic in South Korea: An observational study

Sukhyun Ryu  1 , Dasom Kim  1 , Lae Young Jung  2   3 , Baekjin Kim  1 , Chang-Seop Lee  2   3
Affiliations
Observational Study

Decreased door-to-balloon time in patients with ST-segment elevation myocardial infarction during the early COVID-19 pandemic in South Korea: An observational study

Sukhyun Ryu et al. Medicine (Baltimore). .

Abstract

The coronavirus disease 2019 (COVID-19) resulted in a marked decrease in the number of patient visits for acute myocardial infarction and delayed patient response and intervention in several countries. This study evaluated the effect of the COVID-19 pandemic on the number of patients, patient response time (pain-to-door), and intervention time (door-to-balloon) for patients with ST-segment elevation myocardial infarction (STEMI) and non-ST-segment elevation myocardial infarction (NSTEMI). Patients with STEMI or NSTEMI visiting a hospital in South Korea who underwent primary coronary intervention during the COVID-19 pandemic (January 29, 2020, to December 31, 2020) were compared with those in the equivalent period from 2018 to 2019. Patient response and intervention times were compared for the COVID-19 pandemic window (2020) and the equivalent period from 2018 to 2019. We observed no decrease in the number of patients with STEMI (P = .88) and NSTEMI (P = 1.00) during the COVID-19 pandemic compared to that in the previous years. Patient response times (STEMI: P = .39; NSTEMI: P = .59) during the overall COVID-19 pandemic period did not differ significantly. However, we identified a significant decrease in door-to-balloon time among patients with STEMI (14%; P < .01) during the early COVID-19 pandemic. We found that the number of patients with STEMI and NSTEMI was consistent during the COVID-19 pandemic and that no time delays in patient response and intervention occurred. However, the door-to-balloon time among patients with STEMI significantly reduced during the early COVID-19 pandemic, which could be attributed to decreased emergency care utilization during the early pandemic.

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Conflict of interest statement

The authors have no conflicts of interest to disclose. The authors have no financial conflicts of interest.

Figures

Figure 1.
Figure 1.
COVID-19 cases and estimated rate ratio of hospitalized patients with STEMI and NSTEMI. (A) The weekly count of local COVID-19 cases nationwide (black bar) and in the North Jeolla province (solid blue line). (B) The 2018/2019–2020 estimated admission rate ratio of patients with STEMI (brown bar) and NSTEMI (blue bar) during the 3 different epidemic periods of COVID-19. The bar indicates 95% confidence intervals. The study period included Period-1 (epidemiological week 4–19), Period-2 (week 20–33), and Period-3 (week 34–52). COVID-19, coronavirus disease 2019, NSTEMI = non-ST-segment elevation myocardial infarction, STEMI = ST-segment elevation myocardial infarction.
Figure 2.
Figure 2.
Pain-to-door and door-to-reperfusion times of patients with STEMI and NSTEMI during 3 different periods. The study period included Period-1 (epidemiological week of 4–19), Period-2 (week of 20–33), and Period-3 (week of 34–52). NSTEMI = non-ST-segment elevation myocardial infarction, STEMI = ST-segment elevation myocardial infarction.
See this image and copyright information in PMC

References

    1. European society of cardiology. Fear of COVID-19 keeping more than half of heart attack patients away from hospitals. In: cardiology Eso, ed. 2020. Available at : https://www.escardio.org/The-ESC/Press-Office/Press-releases/Fear-of-COV... [access date July 19, 2022].
    1. Ferreira D, Graffen S, Watkins B, et al. . Effects of lockdown on acute coronary syndrome incidence in an area without community transmission of COVID-19. Open Heart. 2021;8:e001692.
    1. Solomon MD, McNulty EJ, Rana JS, et al. . The Covid-19 pandemic and the incidence of acute myocardial infarction. N Engl J Med. 2020;383:691–3. - PubMed
    1. Wu J, Mamas M, Rashid M, et al. . Patient response, treatments, and mortality for acute myocardial infarction during the COVID-19 pandemic. Eur Heart J Qual Care Clin Outcomes. 2021;7:238–46. - PMC - PubMed
    1. Ibanez B, James S, Agewall S, et al. . 2017 ESC Guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation: the task force for the management of acute myocardial infarction in patients presenting with ST-segment elevation of the European Society of Cardiology (ESC). Eur Heart J. 2018;39:119–77. - PubMed

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