Polycystin-2 in the Endoplasmic Reticulum: Bending Ideas about the Role of the Cilium
- PMID: 35906088
- PMCID: PMC9342637
- DOI: 10.1681/ASN.2022050557
Polycystin-2 in the Endoplasmic Reticulum: Bending Ideas about the Role of the Cilium
Keywords: IP3 receptor; calcium; cilium; endoplasmic reticulum; polycystic kidney disease; polycystin-2.
Comment on
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Channel Function of Polycystin-2 in the Endoplasmic Reticulum Protects against Autosomal Dominant Polycystic Kidney Disease.J Am Soc Nephrol. 2022 Aug;33(8):1501-1516. doi: 10.1681/ASN.2022010053. Epub 2022 Jul 14. J Am Soc Nephrol. 2022. PMID: 35835458 Free PMC article.
References
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- Praetorius HA, Spring KR: Bending the MDCK cell primary cilium increases intracellular calcium. J Membr Biol 184: 71–79, 2001 - PubMed
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- Nauli SM, Alenghat FJ, Luo Y, Williams E, Vassilev P, Li X, et al. : Polycystins 1 and 2 mediate mechanosensation in the primary cilium of kidney cells. Nat Genet 33: 129–137, 2003 - PubMed
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