SGLT2 Inhibitors-A Medical Revelation: Molecular Signaling of Canagliflozin Underlying Hypertension and Vascular Remodeling
- PMID: 35906180
- PMCID: PMC9375488
- DOI: 10.1161/JAHA.122.026774
SGLT2 Inhibitors-A Medical Revelation: Molecular Signaling of Canagliflozin Underlying Hypertension and Vascular Remodeling
Keywords: Editorials; heart failure; high blood pressure; hypertension; mechanisms; myocardial infarction.
Comment on
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Sodium-Glucose Cotransporter 2 Inhibitor Canagliflozin Antagonizes Salt-Sensitive Hypertension Through Modifying Transient Receptor Potential Channels 3 Mediated Vascular Calcium Handling.J Am Heart Assoc. 2022 Aug 2;11(15):e025328. doi: 10.1161/JAHA.121.025328. Epub 2022 Jul 29. J Am Heart Assoc. 2022. PMID: 35904193 Free PMC article.
References
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- Wan N, Fujisawa Y, Kobara H, Masaki T, Nakano D, Rahman A, Nishiyama A. Effects of an SGLT2 inhibitor on the salt sensitivity of blood pressure and sympathetic nerve activity in a nondiabetic rat model of chronic kidney disease. Hypertens Res. 2020;43:492–499. doi: 10.1038/s41440-020-0410-8 - DOI - PubMed
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